Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4375177 | 0.81 | TUBB1 (0.38) | TUBB1MMP1MMP13 | |
| SCHEMBL6805842 | 0.80 | TUBB1 (0.40) | TUBB1ADAM17MMP1MMP13BRD4 | |
| SCHEMBL4367494 | 0.78 | TUBB1 (0.57) | TUBB1ADAM17MMP1 | |
| SCHEMBL6674391 | 0.71 | TUBB1 (0.47) | TUBB1 | |
| SCHEMBL6260958 | 0.71 | TUBB1 (0.41) | TUBB1 | |
| SCHEMBL6672372 | 0.69 | TUBB1 (0.38) | TUBB1MMP1 | |
| SCHEMBL6671859 | 0.68 | TUBB1 (0.44) | TUBB1 | |
| SCHEMBL8224116 | 0.67 | TUBB1 (0.63) | TUBB1 | |
| SCHEMBL4371526 | 0.67 | TUBB1 (0.54) | TUBB1ADAM17MMP1 | |
| SCHEMBL4371978 | 0.66 | TUBB1 (0.63) | TUBB1ADAM17MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016958-A2 | COMPOUNDS FOR TREATING TUMORS | WYETH HOLDINGS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |