SCHEMBL6288400

SCHEMBL6288400

O=C(O)CCOc1cc(Cl)c(Cl)cc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.51
MCL1 Q07820 1/20 0.50
RAB9A P51151 1/20 0.47
PTGDR2 Q9Y5Y4 2/20 0.46
TSHR P16473 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
FKBP1A P62942 1/20 0.43
PPARG P37231 1/20 0.43
KMO O15229 1/20 0.42
MAPK1 P28482 1/20 0.42
NR1I2 O75469 1/20 0.42
ADRA2A P08913 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
TACR2 P21452 1/20 0.42
DRD1 P21728 1/20 0.42
SLC6A2 P23975 1/20 0.42
HTR2A P28223 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381732 0.92 RAB9A (0.54) LMNARAB9APTGDR2TSHRTDP1
SCHEMBL117098 0.92 RAB9A (0.54) LMNARAB9APTGDR2TSHRTDP1
SCHEMBL5339875 0.89 LMNA (0.49) LMNARAB9APTGDR2TSHRTDP1
SCHEMBL1117054 0.83 LMNA (0.50) LMNARAB9ATSHRTDP1L3MBTL1
SCHEMBL11457374 0.81 LMNA (0.49) LMNARAB9ATSHRTDP1L3MBTL1
SCHEMBL11330548 0.80 PTGDR2 (0.56) LMNAMCL1RAB9APTGDR2TSHR
SCHEMBL1496045 0.80 TDP1 (0.70) RAB9APTGDR2TSHRTDP1L3MBTL1
2,4,5-Trichlorophenoxyacetic Acid SCHEMBL30445640 0.80 TDP1 (0.65) LMNAMCL1RAB9APTGDR2TSHR
2,4,5-Trichlorophenoxyacetic Acid SCHEMBL117704 0.80 TDP1 (0.65) LMNAMCL1RAB9APTGDR2TSHR
2,4,5-Trichlorophenoxyacetic Acid SCHEMBL4864791 0.80 TDP1 (0.65) LMNAMCL1RAB9APTGDR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109283276-B Gas chromatography for determining residues of eight phenoxy carboxylic acid herbicides in corn 丁立平 2021-05-07 CN claimed
US-20050148683-A1 Building material having an aggregate processed to remove contaminants therein REID-GREE JOHN D (US) 2005-07-07 US claimed
US-5851546-A Polymer composition for controlled release of active ingredients in response to pH, and a process of preparing the same COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1998-12-22 US claimed
EP-0510080-A4 PRODRUG ANHYDRIDES OF ASPRIN, INDOMETHACIN AND IBUPROFEN, THEIR PREPARATION, COMPOSITIONS, AND ANTI-INFLAMMATORY METHOD OF USE 1992-12-02 EP claimed
EP-0510080-A1 PRODRUG ANHYDRIDES OF ASPRIN, INDOMETHACIN AND IBUPROFEN, THEIR PREPARATION, COMPOSITIONS, AND ANTI-INFLAMMATORY METHOD OF USE NOVA PHARMACEUTICAL CORPORATION (US) 1992-10-28 EP claimed
WO-1991009831-A1 PRODRUG ANHYDRIDES OF ASPRIN, INDOMETHACIN AND IBUPROFEN, THEIR PREPARATION, COMPOSITIONS, AND ANTI-INFLAMMATORY METHOD OF USE NOVA PHARMACEUTICAL CORPORATION (US) 1991-07-11 WO claimed
US-20240254026-A1 METHODS AND SYSTEMS FOR TREATING WASTEWATER REDHORSE CONSTRUCTORS, INC. 2024-08-01 US disclosed
US-11878925-B2 Methods and systems for treating wastewater REDHORSE CONSTRUCTORS, INC. (US) 2024-01-23 US disclosed
CN-109283276-B Gas chromatography for determining residues of eight phenoxy carboxylic acid herbicides in corn 丁立平 2021-05-07 CN disclosed
US-20210024394-A1 METHODS AND SYSTEMS FOR TREATING WASTEWATER REDHORSE CONSTRUCTORS, INC. 2021-01-28 US disclosed
US-8187882-B2 Regenerating transgenic crop plants from meristematic tissues cultured in dikegulac; enhancing soybean and cotton production MONSANTO TECHNOLOGY LLC (US) 2012-05-29 US disclosed
US-20050183160-A1 Novel multiple shoot proliferation and regeneration system for plants BURNS JOHN A (US) 2005-08-18 US disclosed
US-20050148683-A1 Building material having an aggregate processed to remove contaminants therein REID-GREE JOHN D (US) 2005-07-07 US disclosed
US-4098598-A PLANT GROWTH REGULATORS HOFFMANN-LA ROCHE INC. (US) 1978-07-04 US disclosed
US-4094664-A 6-AMINO-O-TOLUIC ACID, HERBICIDES HOFFMANN-LA ROCHE INC. (US) 1978-06-13 US disclosed
US-4093664-A PLANT GROWTH REGULATORS KALO LABORATORIES, INC. (US) 1978-06-06 US disclosed
US-4028089-A BENZOXAZOLINYLIDENE-MALONITRILE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 1977-06-07 US disclosed
US-4014678-A 1-(3,7-Dimethyloctyl)-1(2-propenyl)-and 1(2-propynyl)-piperidinium bromides as plant growth regulants HOFFMANN-LA ROCHE INC. (US) 1977-03-29 US disclosed
US-3940260-A TRICHLOROACETIC ACID, ESTERS OR SALTS AND 2,4-DICHLORO- OR 2,4,5-TRICHLORO- PHENOXYACETIC ACID, ESTERS OR SALTS AMCHEM PRODUCTS, INC. (US) 1976-02-24 US disclosed
US-3940260-A TRICHLOROACETIC ACID, ESTERS OR SALTS AND 2,4-DICHLORO- OR 2,4,5-TRICHLORO- PHENOXYACETIC ACID, ESTERS OR SALTS AMCHEM PRODUCTS, INC. (US) 1976-02-24 US disclosed