Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL1698310 | 0.97 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1FFAR3LCKFYN | |
| Trifluoromethanesulfonic Acid SCHEMBL17318233 | 0.97 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1FFAR3LCKFYN | |
| Trifluoromethanesulfonic Acid SCHEMBL10796158 | 0.97 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1FFAR3LCKFYN | |
| Trifluoromethanesulfonic Acid SCHEMBL1663542 | 0.97 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1FFAR3LCKFYN | |
| Trifluoromethanesulfonic Acid SCHEMBL17508492 | 0.94 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1FFAR3LCKFYN | |
| Trifluoromethanesulfonic Acid SCHEMBL261406 | 0.92 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1FFAR3LCKFYN | |
| Trifluoromethanesulfonic Acid SCHEMBL5093696 | 0.92 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1FFAR3LCKFYN | |
| Trifluoromethanesulfonic Acid SCHEMBL7647499 | 0.88 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1CA1CA2CA7 | |
| Trifluoromethanesulfonic Acid SCHEMBL2167128 | 0.87 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1FFAR3LCKFYN | |
| Trifluoromethanesulfonic Acid SCHEMBL8369202 | 0.84 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916963-B2 | Process using water tolerant Lewis acids in catalytic hydration of alkylene oxides to alkylene glycols | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2005-07-12 | — | — | US | claimed |
| US-20050014980-A1 | Process using water tolerant lewis acids in catalytic hydration of alkylene oxides to alkylene glycols | SAUDI BASIC INDUSTRIES CORPORATION | 2005-01-20 | — | — | US | claimed |
| US-6916963-B2 | Process using water tolerant Lewis acids in catalytic hydration of alkylene oxides to alkylene glycols | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2005-07-12 | — | — | US | disclosed |
| US-6916963-B2 | Process using water tolerant Lewis acids in catalytic hydration of alkylene oxides to alkylene glycols | SAUDI BASIC INDUSTRIES CORPORATION (SA) | 2005-07-12 | — | — | US | disclosed |
| US-20050014980-A1 | Process using water tolerant lewis acids in catalytic hydration of alkylene oxides to alkylene glycols | SAUDI BASIC INDUSTRIES CORPORATION | 2005-01-20 | — | — | US | disclosed |
| US-20050014980-A1 | Process using water tolerant lewis acids in catalytic hydration of alkylene oxides to alkylene glycols | SAUDI BASIC INDUSTRIES CORPORATION | 2005-01-20 | — | — | US | disclosed |