Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL1663542

CC(=O)O.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.52

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Trifluoromethanesulfonic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
FFAR3 O14843 1/20 0.44
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA7 P43166 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
F2 P00734 2/20 0.31
PRSS1 P07477 2/20 0.31
PRSS2 P07478 2/20 0.31
PRSS3 P35030 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL17318233 1.00 ALDH1A1 (0.52) ALDH1A1L3MBTL1FFAR3LCKFYN
Trifluoromethanesulfonic Acid SCHEMBL1698310 1.00 ALDH1A1 (0.52) ALDH1A1L3MBTL1FFAR3LCKFYN
Trifluoromethanesulfonic Acid SCHEMBL10796158 1.00 ALDH1A1 (0.52) ALDH1A1L3MBTL1FFAR3LCKFYN
Trifluoromethanesulfonic Acid SCHEMBL6288403 0.97 ALDH1A1 (0.50) ALDH1A1L3MBTL1FFAR3LCKFYN
Trifluoromethanesulfonic Acid SCHEMBL17508492 0.97 ALDH1A1 (0.50) ALDH1A1L3MBTL1FFAR3LCKFYN
Trifluoromethanesulfonic Acid SCHEMBL5093696 0.94 ALDH1A1 (0.48) ALDH1A1L3MBTL1FFAR3LCKFYN
Trifluoromethanesulfonic Acid SCHEMBL261406 0.94 ALDH1A1 (0.48) ALDH1A1L3MBTL1FFAR3LCKFYN
Trifluoromethanesulfonic Acid SCHEMBL7647499 0.90 ALDH1A1 (0.48) ALDH1A1L3MBTL1CA1CA2CA7
Trifluoromethanesulfonic Acid SCHEMBL2167128 0.89 ALDH1A1 (0.44) ALDH1A1L3MBTL1FFAR3LCKFYN
Trifluoromethanesulfonic Acid SCHEMBL28053484 0.85 ALDH1A1 (0.43) ALDH1A1L3MBTL1CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016069722-A1 IONIC CROSS-LINKED POLYMERIC FILMS FOR GAS SEPARATION CARNEGIE MELLON UNIVERSITY (US) 2016-05-06 WO claimed
US-8906135-B1 Method of purifying a gas stream using 1,2,3-triazolium ionic liquids U.S. DEPARTMENT OF ENERGY (US) 2014-12-09 US claimed
CN-110757682-A Method for recycling waste circuit boards in full-component mode through two-step method 中国科学院山西煤炭化学研究所 2020-02-07 CN disclosed
US-10300438-B2 Ionic cross-linked polymeric films for gas separation CARNEGIE MELLON UNIVERSITY (US) 2019-05-28 US disclosed
US-9890315-B2 Use of polylysine as a shale inhibitor BASF SE (DE) 2018-02-13 US disclosed
US-20180021742-A1 Ionic Cross-Linked Polymeric Films for Gas Separation U.S. DEPARTMENT OF ENERGY 2018-01-25 US disclosed
EP-2737000-B1 USE OF HYPERBRANCHED POLYLYSINE AS SHALE INHIBITOR BASF SE (DE) 2017-06-07 EP disclosed
WO-2016069722-A1 IONIC CROSS-LINKED POLYMERIC FILMS FOR GAS SEPARATION CARNEGIE MELLON UNIVERSITY (US) 2016-05-06 WO disclosed
CN-103917623-A Use of hyperbranched polylysine as shale inhibitor BASF SE 2014-07-09 CN disclosed
EP-2737000-A1 USE OF HYPERBRANCHED POLYLYSINE AS SHALE INHIBITOR BASF SE (DE) 2014-06-04 EP disclosed
US-20130123148-A1 USE OF POLYLYSINE AS A SHALE INHIBITOR BASF SE (DE) 2013-05-16 US disclosed
WO-2013013889-A1 USE OF HYPERBRANCHED POLYLYSINE AS SHALE INHIBITOR BASF SE (DE) 2013-01-31 WO disclosed
EP-2197868-B1 HYDROXYMETHYLFURFURAL ETHERS FROM SUGARS OR HMF AND MIXED ALCOHOLS FURANIX TECHNOLOGIES BV (NL) 2011-04-27 EP disclosed
EP-1915345-A1 FLUORO SUBSTITUTED 2-OXO AZEPAN DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 2008-04-30 EP disclosed
WO-2007020190-A1 FLUORO SUBSTITUTED 2-OXO AZEPAN DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2007-02-22 WO disclosed
US-20050043379-A1 LTA4H Modulators JANSSEN PHARMACEUTICA, N.V. (BE) 2005-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043379-A1 LTA4H Modulators LTA4H, LTB4R, LTB4R2 ALDH1A1 1306/4885L3MBTL1 1782/4885FFAR3 290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.