Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14957448 | 0.78 | ADRA2C (0.44) | CYP2D6TAAR1ADRA2AADRA2CLMNA | |
| SCHEMBL6288575 | 0.76 | TAAR1 (0.40) | CYP2D6TAAR1ADRA2AADRA2CLMNA | |
| SCHEMBL7781865 | 0.76 | TAAR1 (0.39) | CYP2D6TAAR1ADRA2AADRA2CLMNA | |
| SCHEMBL5107698 | 0.76 | TAAR1 (0.39) | CYP2D6TAAR1ADRA2AADRA2CLMNA | |
| SCHEMBL14401159 | 0.74 | ADRA2C (0.41) | CYP2D6TAAR1ADRA2AADRA2CLMNA | |
| SCHEMBL908216 | 0.71 | TAAR1 (0.50) | CYP2D6TAAR1ADRA2AADRA2CLMNA | |
| Isopropylbenzene SCHEMBL87809 | 0.71 | TAAR1 (0.50) | CYP2D6TAAR1ADRA2AADRA2CLMNA | |
| Isopropylbenzene SCHEMBL6568 | 0.71 | — | — | |
| SCHEMBL7499823 | 0.71 | TAAR1 (0.50) | CYP2D6TAAR1ADRA2AADRA2CLMNA | |
| Isopropylbenzene SCHEMBL8431863 | 0.71 | TAAR1 (0.50) | CYP2D6TAAR1ADRA2AADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137820-A1 | Phosphorus compounds | SANDOZ LTD. (CH) | 2002-09-26 | — | — | US | claimed |
| CN-108586520-B | Method for synthesizing organic phosphine compound by using black phosphorus | 中国科学院深圳先进技术研究院 | 2020-07-03 | — | — | CN | disclosed |
| US-6864304-B2 | Phosphorus compounds | CLARIANT FINANCE (BVI) LIMITED (VG) | 2005-03-08 | — | — | US | disclosed |
| US-20020137820-A1 | Phosphorus compounds | SANDOZ LTD. (CH) | 2002-09-26 | — | — | US | disclosed |
| US-6369140-B1 | POLYOLEFIN AND PHOSPHINE OR PHOSPHORANE COMPOUNDS STABILIZERS; OXIDATION, HEAT, STRESS, AND ULTRAVIOLET RADIATION RESISTANCE | CLARIANT FINANCE (BVI) LIMITED (BV) | 2002-04-09 | — | — | US | disclosed |
| US-5488079-A | HEAT AND LIGHT STABILIZERS FOR OLEFINS USING PHOSPHINES | SANDOZ LTD. (CH) | 1996-01-30 | — | — | US | disclosed |