SCHEMBL6288575

SCHEMBL6288575

CC(c1ccccc1)P(c1ccccc1)C(C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.40
CYP3A4 P08684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
CYP2D6 P10635 1/20 0.38
LMNA P02545 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 1/20 0.38
NOS2 P35228 1/20 0.38
ALDH1A1 P00352 1/20 0.37
DPP4 P27487 2/20 0.36
F2 P00734 1/20 0.36
TSHR P16473 1/20 0.36
MIF P14174 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5107698 0.80 TAAR1 (0.39) TAAR1CYP3A4TDP1ADRA2AADRA2C
SCHEMBL7781865 0.80 TAAR1 (0.39) TAAR1CYP3A4TDP1ADRA2AADRA2C
SCHEMBL6288561 0.76 CYP2D6 (0.48) TAAR1ADRA2AADRA2CCYP2D6LMNA
SCHEMBL301059 0.76 TDP1 (0.45) TAAR1CYP3A4TDP1CYP2D6LMNA
SCHEMBL1241416 0.74 TDP1 (0.43) TAAR1CYP3A4TDP1CYP2D6
SCHEMBL5596879 0.72 CYP3A4 (0.41) CYP3A4TDP1ADRA2AADRA2CCYP2D6
SCHEMBL14957448 0.72 ADRA2C (0.44) TAAR1CYP3A4ADRA2AADRA2CCYP2D6
SCHEMBL9330599 0.70 LMNA (0.41) CYP3A4TDP1ADRA2AADRA2CCYP2D6
SCHEMBL4398254 0.70 TDP1 (0.39) TAAR1CYP3A4TDP1
SCHEMBL6569417 0.68 LMNA (0.38) TAAR1CYP3A4TDP1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020137820-A1 Phosphorus compounds SANDOZ LTD. (CH) 2002-09-26 US claimed
US-10103401-B2 Polymer electrolyte composition and polymer electrolyte membrane, polymer electrolyte membrane with catalyst layer, membrane electrode assembly, and polymer electrolyte fuel cell each using the same TORAY INDUSTRIES, INC. (JP) 2018-10-16 US disclosed
EP-3131145-B1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME TORAY INDUSTRIES (JP) 2018-09-05 EP disclosed
US-20170125832-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME TORAY INDUSTRIES, INC. (JP) 2017-05-04 US disclosed
EP-3131145-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME Toray Industries, Inc. (JP) 2017-02-15 EP disclosed
US-6864304-B2 Phosphorus compounds CLARIANT FINANCE (BVI) LIMITED (VG) 2005-03-08 US disclosed
US-20020137820-A1 Phosphorus compounds SANDOZ LTD. (CH) 2002-09-26 US disclosed
US-6369140-B1 POLYOLEFIN AND PHOSPHINE OR PHOSPHORANE COMPOUNDS STABILIZERS; OXIDATION, HEAT, STRESS, AND ULTRAVIOLET RADIATION RESISTANCE CLARIANT FINANCE (BVI) LIMITED (BV) 2002-04-09 US disclosed
US-5488079-A HEAT AND LIGHT STABILIZERS FOR OLEFINS USING PHOSPHINES SANDOZ LTD. (CH) 1996-01-30 US disclosed