Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.85 |
| ▸ | FKBP1A | P62942 | 15/20 | 0.55 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.42 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6288567 | 1.00 | PIN1 (0.85) | PIN1FKBP1AABCC1FKBP4FKBP5 | |
| SCHEMBL6277156 | 0.92 | PIN1 (1.00) | PIN1FKBP1AABCC1FKBP4FKBP5 | |
| SCHEMBL6332062 | 0.81 | PIN1 (1.00) | PIN1FKBP1A | |
| SCHEMBL6274567 | 0.80 | PIN1 (1.00) | PIN1FKBP1AABCC1FKBP4FKBP5 | |
| SCHEMBL6272443 | 0.78 | PIN1 (0.74) | PIN1 | |
| SCHEMBL6326675 | 0.76 | PIN1 (0.69) | PIN1FKBP1AABCC1FKBP4FKBP5 | |
| SCHEMBL7228304 | 0.69 | FKBP1A (0.77) | PIN1FKBP1A | |
| SCHEMBL5966132 | 0.69 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL5965876 | 0.68 | FKBP1A (1.00) | FKBP1A | |
| SCHEMBL6274827 | 0.68 | PIN1 (0.59) | PIN1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603926-A1 | PHOSPHATE/SULFATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN INTERACTING NIMA (PIN1) | PFIZER INC. (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PFIZER INC. | 2005-11-10 | — | — | US | disclosed |
| WO-2004087720-A1 | PHOSPHATE/SULFATE ESTER COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN INTERACTING NIMA (PIN1) | PFIZER INC. (US) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250742-A1 | Phosphate/sulfate ester compounds and pharmaceutical composition for inhibiting protein interacting NIMA (PIN1) | PIN1, PSTPIP2, NIM1K | PIN1 1/4885FKBP1A 21/4885ABCC1 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.