Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 5/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6288673 | 0.77 | HDAC4 (0.40) | HDAC4HDAC6WNT3A | |
| SCHEMBL13937556 | 0.75 | CTSS (0.45) | HDAC4HDAC6CTSS | |
| SCHEMBL3869252 | 0.74 | KDM4E (0.41) | HDAC4HDAC6S1PR1POLBKDM4E | |
| SCHEMBL8360108 | 0.73 | CTSS (0.43) | HDAC4HDAC6CTSS | |
| SCHEMBL6077337 | 0.73 | CTSS (0.43) | HDAC4HDAC6CTSS | |
| SCHEMBL3869248 | 0.72 | HDAC4 (0.39) | HDAC4HDAC6S1PR1POLBKDM4E | |
| SCHEMBL6077329 | 0.70 | CTSS (0.41) | HDAC4HDAC6CTSS | |
| SCHEMBL8361671 | 0.70 | CTSS (0.41) | HDAC4HDAC6CTSS | |
| SCHEMBL8292288 | 0.68 | CTSS (0.44) | HDAC4HDAC6CTSS | |
| SCHEMBL14563109 | 0.67 | CTSS (0.48) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040142-A9 | NOVEL KETO-OXADIAZOLE DERIVATIVES AS CATHEPSIN INHIBITORS | AVENTIS PHARMA INC (US) | 2005-06-09 | — | — | WO | claimed |