Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4793452 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL6289256 | 0.82 | MAPK1 (0.41) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| Oxalic Acid SCHEMBL4772888 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| Oxalic Acid SCHEMBL4772880 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL4770738 | 0.79 | MAPK1 (0.42) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL4774231 | 0.79 | PRMT5 (0.42) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL6289203 | 0.79 | PIK3CA (0.40) | ALDH1A1L3MBTL1KDM4EGAAMAPK1 | |
| Hydrochloric Acid SCHEMBL4771070 | 0.78 | MAPK1 (0.42) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL4772442 | 0.78 | PIK3CA (0.39) | ALDH1A1KMT2AL3MBTL1KDM4EGAA | |
| SCHEMBL4792970 | 0.77 | MAPT (0.41) | ALDH1A1KMT2AMEN1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875761-B2 | Certain 1,3-disubstituted isoquinoline derivatives | EISAI CO., LTD. (JP) | 2005-04-05 | — | — | US | disclosed |