Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6291611 | 0.93 | ESR1 (0.47) | ALDH1A1HSD17B10GPR3ESR1ADRA2A | |
| SCHEMBL10606596 | 0.85 | GPR3 (0.48) | MAPK1HTTALDH1A1HSD17B10GPR3 | |
| SCHEMBL8963308 | 0.84 | CNR1 (0.44) | SKP2CA2 | |
| SCHEMBL9485320 | 0.79 | SKP2 (0.52) | SKP2HPGDMAPK1HTTNPC1 | |
| SCHEMBL8963310 | 0.78 | SKP2 (0.47) | SKP2HPGDMAPK1HTTNPC1 | |
| SCHEMBL28004760 | 0.78 | SKP2 (0.50) | SKP2HPGDMAPK1HTTNPC1 | |
| SCHEMBL11366320 | 0.76 | SKP2 (0.58) | SKP2HPGDMAPK1HTTNPC1 | |
| SCHEMBL5054848 | 0.76 | SKP2 (0.48) | SKP2HPGDMAPK1HTTNPC1 | |
| SCHEMBL8963311 | 0.74 | SKP2 (0.47) | SKP2HPGDMAPK1HTTNPC1 | |
| SCHEMBL20779043 | 0.74 | SKP2 (0.47) | SKP2HPGDMAPK1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020137820-A1 | Phosphorus compounds | SANDOZ LTD. (CH) | 2002-09-26 | — | — | US | claimed |
| US-6864304-B2 | Phosphorus compounds | CLARIANT FINANCE (BVI) LIMITED (VG) | 2005-03-08 | — | — | US | disclosed |
| US-20020137820-A1 | Phosphorus compounds | SANDOZ LTD. (CH) | 2002-09-26 | — | — | US | disclosed |
| US-6369140-B1 | POLYOLEFIN AND PHOSPHINE OR PHOSPHORANE COMPOUNDS STABILIZERS; OXIDATION, HEAT, STRESS, AND ULTRAVIOLET RADIATION RESISTANCE | CLARIANT FINANCE (BVI) LIMITED (BV) | 2002-04-09 | — | — | US | disclosed |
| US-5488079-A | HEAT AND LIGHT STABILIZERS FOR OLEFINS USING PHOSPHINES | SANDOZ LTD. (CH) | 1996-01-30 | — | — | US | disclosed |