Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SKP2 | Q13309 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8963310 | 0.84 | SKP2 (0.47) | SKP2TYRHPGDHTTNPC1 | |
| SCHEMBL8963358 | 0.83 | CNR1 (0.45) | SKP2NPC1RAB9ACA2ALOX5 | |
| SCHEMBL9485320 | 0.81 | SKP2 (0.52) | SKP2TYRHPGDHTTNPC1 | |
| SCHEMBL28004760 | 0.79 | SKP2 (0.50) | SKP2TYRHPGDHTTNPC1 | |
| SCHEMBL5054848 | 0.78 | SKP2 (0.48) | SKP2TYRHPGDHTTNPC1 | |
| SCHEMBL83489 | 0.76 | SKP2 (0.61) | SKP2TYRHPGDHTTNPC1 | |
| SCHEMBL83606 | 0.76 | TYR (0.69) | SKP2TYRHPGDHTTNPC1 | |
| SCHEMBL9734644 | 0.75 | SKP2 (0.50) | SKP2TYRHPGDHTTNPC1 | |
| SCHEMBL8561136 | 0.75 | CYP3A4 (0.50) | TYRHTTMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL6288736 | 0.74 | SKP2 (0.46) | SKP2TYRHPGDHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5481049-A | REACTING CONJUGATED DIENE AND WATER IN PRESENCE OF CARBON DIOXIDE, USING PALLADIUM COMPOUND AND A FREE PHOSPHINE AS CATALYSTS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-01-02 | — | — | US | disclosed |