Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680102 | 0.93 | KCNH3 (0.46) | DDB1CRBNKCNH3MEN1CYP1A2 | |
| SCHEMBL10977584 | 0.82 | POLB (0.40) | CYP1A2KMT2AALDH1A1MAPT | |
| SCHEMBL15921255 | 0.82 | DDB1 (0.50) | DDB1CRBN | |
| SCHEMBL15933095 | 0.82 | TDP1 (0.46) | ALDH1A1 | |
| SCHEMBL15921072 | 0.82 | HSD17B10 (0.40) | HSD17B10 | |
| SCHEMBL7039605 | 0.80 | DDB1 (0.55) | DDB1CRBNKCNH3CYP1A2ALDH1A1 | |
| SCHEMBL4318982 | 0.80 | KDM4E (0.43) | MEN1KMT2A | |
| SCHEMBL878297 | 0.78 | MAPT (0.42) | MEN1KMT2AHSD17B10ALDH1A1MAPT | |
| SCHEMBL17845542 | 0.78 | DDB1 (0.40) | DDB1CRBNKCNH3ALDH1A1MAPT | |
| SCHEMBL17845380 | 0.78 | DDB1 (0.40) | DDB1CRBNKCNH3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0348351-A1 | Process for the preparation of substituted anilides | CIBA-GEIGY AG (CH) | 1989-12-27 | — | — | EP | claimed |
| EP-0046138-B1 | PROCESS FOR THE PREPARATION OF 3-(N-ARYLAMINO)-TETRAHYDROTHIOPHEN-2-ONE DERIVATIVES | CIBA-GEIGY AG (CH) | 1985-12-04 | — | — | EP | claimed |
| US-4368327-A | REACTION OF CORRESPONDING FURANONE WITH SALT OF THIOCARBOXYLIC ACID | CIBA-GEIGY CORPORATION (US) | 1983-01-11 | — | — | US | claimed |
| JP-2045480-A | — | — | None | — | — | JP | disclosed |
| US-6956055-B2 | Substituted γ-lactone compounds as NMDA-antagonists | GRUNENTHAL GMBH (DE) | 2005-10-18 | — | — | US | disclosed |
| JP-H0245480-A | PRODUCTION OF SUBSTITUTED ANILIDES | CIBA GEIGY AG | 1990-02-15 | — | — | JP | disclosed |
| EP-0348351-A1 | Process for the preparation of substituted anilides | CIBA-GEIGY AG (CH) | 1989-12-27 | — | — | EP | disclosed |
| EP-0348351-A1 | Process for the preparation of substituted anilides | CIBA-GEIGY AG (CH) | 1989-12-27 | — | — | EP | disclosed |
| US-4810724-A | PHYTOPATHOGENS | CIBA-GEIGY CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
| US-4564629-A | N-ACYLATED-N-/PHENYLAMINO/TETRAHYDRO-2-FURANONES | CIBA-GEIGY CORPORATION (US) | 1986-01-14 | — | — | US | disclosed |
| US-4443618-A | N-ACYLATED N-PHENYL-AMINOTETRAHYDRO-2-FURANONE | CIBA-GEIGY CORPORATION (US) | 1984-04-17 | — | — | US | disclosed |
| US-4316909-A | Fungicidal compositions | CIBA-GEIGY CORPORATION (US) | 1982-02-23 | — | — | US | disclosed |
| US-4296118-A | Fungicidal 3-[N-(pyrazol-1-yl-acetyl)-N-(substituted phenyl)]-amino-tetrahydro-2-furanones | CIBA-GEIGY CORPORATION (US) | 1981-10-20 | — | — | US | disclosed |
| US-4276303-A | SYSTEMIC FUNGICIDES FOR PHYTOPATHOGENIC FUNGI | CIBA-GEIGY CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |
| US-4233308-A | PHYTOPATHOGENIC FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4165322-A | 3-(ALKYL-, ALKOXY-, HALO-, OR NITRO-SUBSTITUTED)PHENYLAMINO-GAMMA-BUTYROLACTONE OR BUTYROTHIOLACTONE | CHEVRON RESEARCH COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| US-4147792-A | N-ACYL-N-PHENYLAMINOTETRAHYDRO-2-FURANONE | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |