Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17845602 | 0.83 | KDM4E (0.44) | TRPA1SMN1; SMN2 | |
| SCHEMBL17845716 | 0.80 | FADS1 (0.50) | ALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL17845508 | 0.80 | CYP3A4 (0.39) | TRPA1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6288896 | 0.78 | DDB1 (0.47) | DDB1CRBNALDH1A1MAPTKCNH3 | |
| SCHEMBL17845380 | 0.78 | DDB1 (0.40) | DDB1CRBNTRPA1ALDH1A1MAPT | |
| SCHEMBL17845615 | 0.77 | ROCK2 (0.46) | ALDH1A1MAPT | |
| SCHEMBL3849093 | 0.76 | ADRA2A (0.44) | DDB1CRBNLRRK2 | |
| SCHEMBL3849096 | 0.76 | ADRA2A (0.44) | DDB1CRBNLRRK2 | |
| SCHEMBL17845532 | 0.74 | ROCK2 (0.42) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL17845784 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |