Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 12/20 | 0.56 |
| ▸ | ACHE | P22303 | 5/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthranilamide SCHEMBL6288989 | 0.90 | STING1 (0.49) | STING1ACHEBCL2L1 | |
| SCHEMBL1589579 | 0.88 | STING1 (0.68) | STING1ACHEHDAC3HDAC4HDAC1 | |
| SCHEMBL16396077 | 0.85 | STING1 (0.54) | STING1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30417131 | 0.82 | SRD5A1 (0.57) | STING1ACHE | |
| SCHEMBL30449069 | 0.82 | SRD5A1 (0.57) | STING1ACHE | |
| SCHEMBL23480428 | 0.82 | SRD5A1 (0.57) | STING1ACHE | |
| SCHEMBL21405928 | 0.82 | SRD5A1 (0.57) | STING1ACHE | |
| SCHEMBL6288990 | 0.81 | HDAC1 (0.51) | STING1ACHEHDAC3HDAC4HDAC1 | |
| SCHEMBL6284804 | 0.81 | CA2 (0.49) | BCL2L1 | |
| SCHEMBL31081089 | 0.79 | STING1 (0.60) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005508311-A | — | — | 2005-03-31 | — | — | JP | claimed |
| EP-1416928-A2 | N-MONOACYLATED DERIVATIVES OF O-PHENYLENEDIAMINES, THEIR SIX MEMBERED HETEROCYCLIC ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-12 | — | — | EP | claimed |
| WO-2003013484-A2 | N-MONOACYLATED DERIVATIVES OF O-PHENYLENEDIAMINES, THEIR SIX MEMBERED HETEROCYCLIC ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-02-20 | — | — | WO | claimed |