Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1850788 | 0.91 | CA2 (0.53) | CA2BCL2L1CHRNA7ALDH1A1KDM4E | |
| Anthranilamide SCHEMBL6284801 | 0.90 | CA2 (0.43) | CA2BCL2L1CHRNA7ALDH1A1KDM4E | |
| SCHEMBL15697569 | 0.83 | BCL2L1 (0.46) | CA2BCL2L1CHRNA7ALDH1A1KDM4E | |
| SCHEMBL3252698 | 0.82 | BCL2L1 (0.53) | CA2BCL2L1CHRNA7ALDH1A1KDM4E | |
| SCHEMBL2895989 | 0.81 | ALDH1A1 (0.55) | CA2CHRNA7ALDH1A1KDM4EHPGD | |
| SCHEMBL6284802 | 0.81 | LMNA (0.51) | CA2CHRNA7ALDH1A1KDM4EHPGD | |
| SCHEMBL6288992 | 0.81 | STING1 (0.56) | BCL2L1 | |
| SCHEMBL15697497 | 0.78 | BCL2L1 (0.46) | BCL2L1CHRNA7ALDH1A1KDM4EHPGD | |
| SCHEMBL17842761 | 0.77 | CHRNA7 (0.53) | CA2BCL2L1CHRNA7ALDH1A1KDM4E | |
| SCHEMBL2897570 | 0.77 | CHRNA7 (0.53) | BCL2L1CHRNA7ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005508311-A | — | — | 2005-03-31 | — | — | JP | claimed |
| EP-1416928-A2 | N-MONOACYLATED DERIVATIVES OF O-PHENYLENEDIAMINES, THEIR SIX MEMBERED HETEROCYCLIC ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-12 | — | — | EP | claimed |
| WO-2003013484-A2 | N-MONOACYLATED DERIVATIVES OF O-PHENYLENEDIAMINES, THEIR SIX MEMBERED HETEROCYCLIC ANALOGUES AND THEIR USE AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-02-20 | — | — | WO | claimed |