Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 4/20 | 0.45 |
| ▸ | FNTB | P49356 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628433 | 0.88 | FNTA (0.59) | FNTAFNTB | |
| SCHEMBL630026 | 0.82 | FNTA (0.54) | FNTAFNTB | |
| SCHEMBL628444 | 0.78 | NPSR1 (0.40) | — | |
| SCHEMBL628801 | 0.76 | L3MBTL1 (0.41) | SMN1; SMN2 | |
| SCHEMBL7874204 | 0.75 | FNTA (0.58) | FNTAFNTB | |
| SCHEMBL629703 | 0.73 | FNTA (0.79) | FNTAFNTB | |
| SCHEMBL7874240 | 0.73 | FNTA (0.67) | FNTAFNTB | |
| SCHEMBL629100 | 0.70 | FNTA (0.80) | FNTAFNTB | |
| SCHEMBL629061 | 0.70 | FNTA (0.80) | FNTAFNTB | |
| SCHEMBL628794 | 0.70 | FNTA (0.79) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |