Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 5/20 | 0.54 |
| ▸ | FNTB | P49356 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628433 | 0.93 | FNTA (0.59) | FNTAFNTB | |
| SCHEMBL6625746 | 0.84 | FNTA (0.69) | FNTAFNTB | |
| SCHEMBL630025 | 0.82 | FNTA (0.54) | FNTAFNTB | |
| SCHEMBL628935 | 0.82 | SMN1; SMN2 (0.46) | FNTAFNTB | |
| SCHEMBL628801 | 0.82 | L3MBTL1 (0.41) | ALDH1A1 | |
| SCHEMBL628869 | 0.81 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7909038 | 0.80 | FNTA (0.70) | FNTAFNTB | |
| SCHEMBL7909037 | 0.80 | FNTA (0.70) | FNTAFNTB | |
| SCHEMBL628444 | 0.79 | NPSR1 (0.40) | ALDH1A1 | |
| SCHEMBL629257 | 0.79 | FNTA (0.69) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |