Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4961254 | 0.98 | MGLL (0.39) | MGLLTLR8ACHEGCGRTAAR1 | |
| SCHEMBL31145657 | 0.91 | MGLL (0.43) | MGLLTLR8ACHEGCGRMEN1 | |
| SCHEMBL3904606 | 0.91 | MGLL (0.43) | MGLLTLR8ACHEGCGRMEN1 | |
| SCHEMBL31741939 | 0.90 | MGLL (0.42) | MGLLTLR8ACHEGCGRMEN1 | |
| Tetramethylammonium Ion SCHEMBL7662067 | 0.87 | MGLL (0.40) | MGLLTLR8ACHEGCGRGRM2 | |
| SCHEMBL26327147 | 0.84 | ACHE (0.46) | MGLLTLR8ACHEGCGRNFE2L2 | |
| Tetrabuthylammonium SCHEMBL809813 | 0.84 | MGLL (0.39) | MGLLTLR8GCGRGRM2ICMT | |
| SCHEMBL26287032 | 0.83 | MGLL (0.38) | MGLLTLR8MEN1KMT2A | |
| SCHEMBL26287029 | 0.83 | MGLL (0.38) | MGLLTLR8MEN1KMT2A | |
| SCHEMBL31145634 | 0.82 | MGLL (0.38) | MGLLTLR8GCGRGRM2ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900250-B2 | Polymerizable composition | TOYO INK MFG. CO., LTD. (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20030212162-A1 | Photopolymerization using photoinitiators | TOYO INK MFG. CO., LTD. (JP) | 2003-11-13 | — | — | US | disclosed |