SCHEMBL6289769

SCHEMBL6289769

CCc1ccc(F)c(Oc2ccccc2Oc2cc(CC)ccc2F)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
XBP1 P17861 1/20 0.44
HTT P42858 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
CARM1 Q86X55 3/20 0.42
PRMT6 Q96LA8 3/20 0.42
FAAH O00519 1/20 0.41
HTR1A P08908 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
CYP4F2 P78329 1/20 0.40
CYP4A11 Q02928 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6289267 1.00 XBP1 (0.44) XBP1HTTNPSR1CYP1A2CYP2A6
SCHEMBL6293875 1.00 XBP1 (0.44) XBP1HTTNPSR1CYP1A2CYP2A6
SCHEMBL13888115 0.86 TTR (0.47) CYP1A2CYP2A6SLC6A4
SCHEMBL4457309 0.85 TTR (0.48) XBP1HTTNPSR1CARM1PRMT6
SCHEMBL21971221 0.80 CARM1 (0.48) XBP1HTTNPSR1CARM1PRMT6
SCHEMBL2432106 0.79 PTGS2 (0.52) CYP4F2CYP4A11
SCHEMBL12854897 0.78 SLC6A2 (0.50) XBP1HTTNPSR1CARM1PRMT6
SCHEMBL3207176 0.78 TTR (0.45) XBP1HTTNPSR1CARM1PRMT6
SCHEMBL29703994 0.77 KDM1A (0.48) HTR1ASLC6A2SLC6A4SLC6A3L3MBTL1
SCHEMBL18787264 0.77 KDM1A (0.48) HTR1ASLC6A2SLC6A4SLC6A3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6933411-B2 Aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2005-08-23 US disclosed
US-6737503-B2 LOW TEMPERATURE ADHESIVE BONDING MITSUI CHEMICALS, INC. (JP) 2004-05-18 US disclosed
US-20040082754-A1 Novel aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2004-04-29 US disclosed
US-20030092870-A1 Novel aromatic diamine and polyimide thereof MITSUI CHEMICALS, INC. (JP) 2003-05-15 US disclosed
EP-1288191-A2 Novel aromatic diamine and polyimide thereof Mitsui Chemicals, Inc. (JP) 2003-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030092870-A1 Novel aromatic diamine and polyimide thereof DDT, AOC1, H1-4 XBP1 4616/4885HTT 2649/4885NPSR1 1386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.