Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | NEK2 | P51955 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366889 | 0.80 | MAPT (0.42) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL26631046 | 0.79 | MAPT (0.46) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL65263 | 0.78 | MAPT (0.55) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL4588436 | 0.77 | MAPT (0.44) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL18922435 | 0.77 | MAPT (0.53) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL15658498 | 0.75 | MAPT (0.47) | ALDH1A1MAPTGAATSHRTP53 | |
| Cyclohexane SCHEMBL3588452 | 0.75 | MAPT (0.39) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL3184967 | 0.72 | MAPT (0.44) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL28806634 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTGAATSHRTP53 | |
| SCHEMBL27997994 | 0.72 | TSHR (0.39) | ALDH1A1MAPTGAATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108659534-A | Building template material and preparation method thereof | 湖南辰砾新材料有限公司 | 2018-10-16 | — | — | CN | claimed |
| CN-1890253-A | Process for preparing ortho-metalated and ortho-substituted aromatic compounds | SOLVIAS AG (CH) | 2007-01-03 | — | — | CN | claimed |
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | C4 THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | US | disclosed |
| CN-108659534-A | Building template material and preparation method thereof | 湖南辰砾新材料有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-105754099-B | Composition and polymer | 旭化成株式会社 | 2018-09-18 | — | — | CN | disclosed |
| CN-103502315-B | Composition and polymer | 旭化成株式会社 | 2016-08-17 | — | — | CN | disclosed |
| CN-105754099-A | Composition and polymer | 旭化成株式会社 | 2016-07-13 | — | — | CN | disclosed |
| WO-2016011107-A2 | TRANSITION METAL-BASED SELECTIVE FUNCTIONALIZATION OF CHALCOGENS IN BIOMOLECULES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-21 | — | — | WO | disclosed |
| US-9082990-B2 | Complex compounds having a ligand containing an N donor and a P donor and the use thereof in the opto-electronic field | MERCK PATENT GMBH (DE) | 2015-07-14 | — | — | US | disclosed |
| CN-103328435-B | Process for producing aromatic amide carboxylic acid derivative | MITSUI CHEMICALS AGRO INC | 2015-07-01 | — | — | CN | disclosed |
| US-8981086-B2 | Phosphine-ligated palladium sulfonate palladacycles | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-03-17 | — | — | US | disclosed |
| WO-1997040000-A1 | PROCESSES FOR PRODUCING HYDROXYALDEHYDES | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-10-30 | — | — | WO | disclosed |
| EP-0666255-B1 | Process for the preparation of vitamin A and intermediates | RHONE POULENC NUTRITION ANIMAL (FR) | 1997-10-22 | — | — | EP | disclosed |
| US-5637779-A | CONDENSATING ETHYNYL-B-IONOL WITH AN ACETAL IN PRESENCE OF A COPPER CATALYST AND A BASE; HYDROGENATING; FORMING RETINOL;REDUCTION | RHONE-POULENC NUTRITION ANIMALE (FR) | 1997-06-10 | — | — | US | disclosed |
| WO-1997014668-A1 | OXIDATION OF ALDEHYDES TO CARBOXYLIC ACIDS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-04-24 | — | — | WO | disclosed |
| EP-0666255-A1 | Process for the preparation of vitamin A and intermediates | RHONE-POULENC NUTRITION ANIMALE (FR) | 1995-08-09 | — | — | EP | disclosed |
| EP-0136210-B1 | CHIRAL PHOSPHORUS LIGANDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE CATALYSIS OF ENANTIOSELECTIVE SYNTHESIS REACTIONS | NORSOLOR S.A. (FR) | 1989-08-16 | — | — | EP | disclosed |
| EP-0136210-A1 | Chiral phosphorus ligands, process for their preparation and their use in the catalysis of enantioselective synthesis reactions | NORSOLOR S.A. (FR) | 1985-04-03 | — | — | EP | disclosed |
| US-4469886-A | PALLADIUM CATALYST HAVING PHOSPHOAMINE LIGAND | THE STANDARD OIL COMPANY (US) | 1984-09-04 | — | — | US | disclosed |
| EP-0052419-A1 | Process for the selective hydrocarboxylation of propylene to isobutyric acid | THE STANDARD OIL COMPANY (US) | 1982-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339902-A1 | TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 | IKZF1, IKZF3, IKZF2 | ALDH1A1 4344/4885MAPT 1369/4885GAA 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.