Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | NEK2 | P51955 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL3588452 | 0.94 | MAPT (0.39) | MAPTALDH1A1L3MBTL1NSD2EGFR | |
| SCHEMBL15658498 | 0.85 | MAPT (0.47) | MAPTALDH1A1L3MBTL1NSD2EGFR | |
| SCHEMBL2919461 | 0.85 | MAPT (0.52) | MAPTALDH1A1L3MBTL1NSD2EGFR | |
| SCHEMBL18922435 | 0.83 | MAPT (0.53) | MAPTALDH1A1L3MBTL1NSD2EGFR | |
| SCHEMBL6289829 | 0.80 | ALDH1A1 (0.44) | MAPTALDH1A1L3MBTL1NSD2EGFR | |
| Bromide SCHEMBL28055011 | 0.79 | MAPT (0.42) | MAPTALDH1A1L3MBTL1NSD2EGFR | |
| SCHEMBL21526429 | 0.77 | NSD2 (0.32) | MAPTALDH1A1L3MBTL1NSD2EGFR | |
| SCHEMBL1752721 | 0.77 | MEN1 (0.39) | MAPTALDH1A1L3MBTL1LMNAMAPK1 | |
| SCHEMBL10177351 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1L3MBTL1NSD2EGFR | |
| SCHEMBL3965515 | 0.74 | ALDH1A1 (0.44) | MAPTALDH1A1L3MBTL1NSD2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3461556-A1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | AbbVie Ireland Unlimited Company (IE) | 2019-04-03 | — | — | EP | disclosed |
| EP-2593226-B1 | PHOSPHINE LIGANDS FOR CATALYTIC REACTIONS | ABBVIE IRELAND UNLIMITED CO (IE) | 2018-11-14 | — | — | EP | disclosed |
| CN-107949562-A | The positive allosteric modulators of muscarinic M2 acceptors | 拜耳制药股份公司 | 2018-04-20 | — | — | CN | disclosed |
| US-9809591-B2 | Heterocyclic modulators of lipid synthesis | 3-V BIOSCIENCES, INC. (US) | 2017-11-07 | — | — | US | disclosed |
| EP-3190108-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V Biosciences, Inc. (US) | 2017-07-12 | — | — | EP | disclosed |
| US-9669399-B2 | Phosphine ligands for catalytic reactions | ABBVIE INC. (US) | 2017-06-06 | — | — | US | disclosed |
| US-9669399-B2 | Phosphine ligands for catalytic reactions | ABBVIE INC. (US) | 2017-06-06 | — | — | US | disclosed |
| CN-106661008-A | 2,5-disubstituted cyclopentane carboxylic acids for the treatment of respiratoy tract diseases | 拜耳制药股份公司 | 2017-05-10 | — | — | CN | disclosed |
| US-20170119786-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | SAGIMET BIOSCIENCES INC. | 2017-05-04 | — | — | US | disclosed |
| EP-2683244-B1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V BIOSCIENCES INC (US) | 2017-02-01 | — | — | EP | disclosed |
| CN-1826310-A | Novel aminobenzophenone compounds | LEO PHARMA AS (DK) | 2006-08-30 | — | — | CN | disclosed |
| WO-2006007843-A1 | 2-(1H-INDOLYLSULFANYL) -ARYL AMINE DERIVATIVES FOR USE IN THE TREATMENT OF AFFECTIVE DISORDERS, PAIN, ADHD AND STRESS URINARY INCONTINENCE | H. LUNDBECK A/S (DK) | 2006-01-26 | — | — | WO | disclosed |
| CN-1231459-C | Novel aminobenzophenones | LEO PHARM PROD LTD (DK) | 2005-12-14 | — | — | CN | disclosed |
| CN-1561327-A | Novel aminobenzophenones | LEO PHARMA AS (DK) | 2005-01-05 | — | — | CN | disclosed |
| CN-1181048-C | Aminobenzophenones as inhibitors of IL-1 beta and TNF_alpha | ������˹ҩƷ��˾ | 2004-12-22 | — | — | CN | disclosed |
| CN-1174956-C | Aminobenzophenones as inhibitors of IL-1 beta and TNF-alpha | ������˹ҩƷ��˾ | 2004-11-10 | — | — | CN | disclosed |
| CN-1487924-A | Farnesyl transferase inhibitors | ���Ͽع�����˾ | 2004-04-07 | — | — | CN | disclosed |
| CN-1368950-A | Novel aminobenzophenones | LEO PHARM PROD LTD (DK) | 2002-09-11 | — | — | CN | disclosed |
| CN-1368953-A | Aminobenzophenones as inhibitors of IL-1 bata and TNF-alpha | LEO PHARM PROD LTD (DK) | 2002-09-11 | — | — | CN | disclosed |
| CN-1361763-A | Aminobenzophenones as inhibitors of IL-1 beta and TNF_alpha | LEO PHARM PROD LTD (DK) | 2002-07-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119786-A1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | FASN, FADS1, SCD | MAPT 4329/4885ALDH1A1 724/4885L3MBTL1 2485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.