Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.59 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6291198 | 0.87 | PTGS2 (0.60) | PTGS2PTGS1IDO1 | |
| SCHEMBL6180979 | 0.87 | PTGS2 (0.63) | PTGS2PTGS1IDO1TDO2 | |
| SCHEMBL6294248 | 0.87 | PTGS2 (0.63) | PTGS2PTGS1IDO1TDO2 | |
| SCHEMBL6291219 | 0.87 | PTGS2 (0.58) | PTGS2PTGS1IDO1TDO2 | |
| SCHEMBL5698592 | 0.87 | IDO1 (0.52) | PTGS2PTGS1IDO1TDO2 | |
| SCHEMBL6293882 | 0.86 | IDO1 (0.49) | PTGS2PTGS1IDO1TDO2 | |
| SCHEMBL6291082 | 0.85 | PTGS2 (0.62) | PTGS2PTGS1IDO1TDO2 | |
| SCHEMBL6291197 | 0.85 | PTGS2 (0.62) | PTGS2PTGS1IDO1TDO2 | |
| SCHEMBL6291235 | 0.85 | PTGS2 (0.59) | PTGS2PTGS1IDO1TDO2 | |
| SCHEMBL6419428 | 0.85 | PTGS2 (0.58) | PTGS2PTGS1IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838476-B1 | Cyclooxygenase inhibitors; anticancer agents | J. URIACH & CIA, SA (ES) | 2005-01-04 | — | — | US | claimed |
| EP-1122243-B1 | NOVEL IMIDAZOLES WITH ANTI-INFLAMMATORY ACTIVITY | URIACH Y COMPANIA S A J (ES) | 2004-09-08 | — | — | EP | claimed |
| EP-1122243-A1 | NOVEL IMIDAZOLES WITH ANTI-INFLAMMATORY ACTIVITY | J. URIACH & CIA. S.A. (ES) | 2001-08-08 | — | — | EP | claimed |
| US-6838476-B1 | Cyclooxygenase inhibitors; anticancer agents | J. URIACH & CIA, SA (ES) | 2005-01-04 | — | — | US | disclosed |
| EP-1122243-B1 | NOVEL IMIDAZOLES WITH ANTI-INFLAMMATORY ACTIVITY | URIACH Y COMPANIA S A J (ES) | 2004-09-08 | — | — | EP | disclosed |
| EP-1122243-A1 | NOVEL IMIDAZOLES WITH ANTI-INFLAMMATORY ACTIVITY | J. URIACH & CIA. S.A. (ES) | 2001-08-08 | — | — | EP | disclosed |