SCHEMBL6289875

SCHEMBL6289875

O=C(OC(=O)c1c(S)ccc2ccccc12)c1c(S)ccc2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 2/20 0.42
KMT2A Q03164 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 3/20 0.41
MEN1 O00255 3/20 0.41
HPGD P15428 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
CYP2A6 P11509 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
WDR5 P61964 1/20 0.39
LDHA P00338 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.37
NR4A1 P22736 1/20 0.37
NR4A2 P43354 1/20 0.37
NR4A3 Q92570 1/20 0.37
MAPT P10636 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2200513 0.81 HSD17B10 (0.59) KMT2AALDH1A1HSD17B10MEN1HPGD
SCHEMBL10880498 0.79 ABCG2 (0.53) KMT2AALDH1A1HSD17B10MEN1HPGD
SCHEMBL7658707 0.79 ALDH1A1 (0.42) NCEH1KMT2AALDH1A1HSD17B10MEN1
SCHEMBL1392829 0.79 NCEH1 (0.51) NCEH1KMT2AALDH1A1HSD17B10MEN1
SCHEMBL4960184 0.78 NCEH1 (0.42) NCEH1KMT2AALDH1A1HSD17B10MEN1
SCHEMBL5457127 0.78 NCEH1 (0.42) NCEH1KMT2AALDH1A1HSD17B10MEN1
SCHEMBL4958880 0.78 CYP2A6 (0.48) NCEH1KMT2AALDH1A1HSD17B10MEN1
SCHEMBL4960213 0.78 NCEH1 (0.42) NCEH1KMT2AALDH1A1HSD17B10MEN1
SCHEMBL542536 0.76 WDR5 (0.59) NCEH1KMT2AALDH1A1HSD17B10MEN1
SCHEMBL11463069 0.76 HDAC8 (0.41) NCEH1KMT2AALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6939364-B1 placing tissues in proximity, providing an adhesive with collagen content of 300-800 mg/ml that is gelatinized with thermal energy and derivatized with a carbox group, and exposing to electromagnetic radiation TISSUE ADHESIVE TECHNOLOGIES, INC. (US) 2005-09-06 US disclosed
US-6875427-B1 Light energized tissue adhesive TISSUE ADHESIVE TECHNOLOGIES, INC. (US) 2005-04-05 US disclosed
US-6780840-B1 Method for making a light energized tissue adhesive TISSUE ADHESIVE TECHNOLOGIES, INC. 2004-08-24 US disclosed
US-6773699-B1 Light energized tissue adhesive conformal patch TISSUE ADHESIVE TECHNOLOGIES, INC. 2004-08-10 US disclosed