Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630661 | 0.80 | AR (0.44) | ARPGRIGF1R | |
| SCHEMBL631033 | 0.79 | AR (0.37) | ARPGRPPARGPPARDPPARA | |
| SCHEMBL629441 | 0.78 | AR (0.39) | ARPGRIGF1R | |
| SCHEMBL14735727 | 0.77 | AR (0.39) | ARPGRPPARGPPARDPPARA | |
| SCHEMBL629676 | 0.76 | AR (0.50) | ARPGR | |
| SCHEMBL14735643 | 0.76 | AR (0.40) | ARPGR | |
| SCHEMBL629598 | 0.75 | AR (0.41) | ARPGR | |
| SCHEMBL629322 | 0.74 | AR (0.52) | ARPGR | |
| SCHEMBL629334 | 0.73 | AR (0.38) | ARPGRPPARGPPARDPPARA | |
| SCHEMBL629373 | 0.71 | AR (0.49) | ARPGRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419410-A1 | IMIDAZOLIDINE-2,4-DIONE DERIVATIVES, AND USE THEREOF AS A CANCER DRUG | IPSEN PHARMA S.A.S. (FR) | 2012-02-22 | — | — | EP | disclosed |