Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6294278 | 0.87 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6579922 | 0.87 | PTGS2 (0.47) | PTGS2TSHRPTGS1ALDH1A1MAPT | |
| SCHEMBL6289796 | 0.78 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL6291053 | 0.74 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL8199109 | 0.71 | SMN1; SMN2 (0.50) | PTGS2RAB9ANPC1LMNAMAPK1 | |
| SCHEMBL6291171 | 0.71 | HSP90AA1 (0.45) | PTGS2RAB9ANPC1LMNAMAPK1 | |
| SCHEMBL6290674 | 0.70 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL19953198 | 0.70 | PTGS2 (0.68) | PTGS2RAB9ANPC1LMNAMAPK1 | |
| SCHEMBL19953204 | 0.69 | PTGS2 (0.49) | PTGS2LMNAALDH1A1MAPTHPGD | |
| SCHEMBL13317735 | 0.69 | PTGS2 (0.41) | PTGS2RAB9ANPC1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838476-B1 | Cyclooxygenase inhibitors; anticancer agents | J. URIACH & CIA, SA (ES) | 2005-01-04 | — | — | US | disclosed |
| EP-1122243-B1 | NOVEL IMIDAZOLES WITH ANTI-INFLAMMATORY ACTIVITY | URIACH Y COMPANIA S A J (ES) | 2004-09-08 | — | — | EP | disclosed |
| EP-1122243-A1 | NOVEL IMIDAZOLES WITH ANTI-INFLAMMATORY ACTIVITY | J. URIACH & CIA. S.A. (ES) | 2001-08-08 | — | — | EP | disclosed |