Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290551 | 0.87 | PTGS2 (0.49) | PTGS2PTGS1ALDH1A1TSHRMAPT | |
| SCHEMBL6294278 | 0.86 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6290668 | 0.77 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL19953204 | 0.76 | PTGS2 (0.49) | PTGS2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL8642483 | 0.71 | NPC1 (0.50) | PTGS2PTGS1ALDH1A1MEN1KMT2A | |
| SCHEMBL6294273 | 0.70 | FGFR1 (0.46) | PTGS2PTGS1FGFR1MAOBALDH1A3 | |
| SCHEMBL6291053 | 0.70 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6290674 | 0.69 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL28376155 | 0.68 | HCAR1 (0.38) | PTGS2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL19953198 | 0.68 | PTGS2 (0.68) | PTGS2PTGS1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122243-B1 | NOVEL IMIDAZOLES WITH ANTI-INFLAMMATORY ACTIVITY | URIACH Y COMPANIA S A J (ES) | 2004-09-08 | — | — | EP | disclosed |
| EP-1122243-A1 | NOVEL IMIDAZOLES WITH ANTI-INFLAMMATORY ACTIVITY | J. URIACH & CIA. S.A. (ES) | 2001-08-08 | — | — | EP | disclosed |