SCHEMBL6290862

SCHEMBL6290862

C=C(C)COCCOC(=O)Oc1ccc(C(C)(C)c2ccc(OC(=O)OCCOCC(=C)C)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.36
POLB P06746 2/20 0.36
ALDH1A1 P00352 7/20 0.35
MEN1 O00255 4/20 0.35
KMT2A Q03164 4/20 0.35
HTT P42858 1/20 0.35
AR P10275 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
ELANE P08246 1/20 0.34
GAA P10253 1/20 0.34
LMNA P02545 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
BCHE P06276 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6295073 0.85 THRB (0.45) KDM4EPOLBALDH1A1MEN1KMT2A
SCHEMBL6290863 0.83 POLB (0.44) KDM4EPOLBALDH1A1MEN1KMT2A
SCHEMBL1833168 0.80 SMN1; SMN2 (0.46) KDM4EPOLBALDH1A1MEN1KMT2A
SCHEMBL10871567 0.76 KMT2A (0.46) POLBALDH1A1MEN1KMT2AHTT
SCHEMBL2273708 0.76 SMN1; SMN2 (0.45) KDM4EPOLBALDH1A1MEN1KMT2A
SCHEMBL11925435 0.75 KMT2A (0.45) KDM4EPOLBALDH1A1MEN1KMT2A
SCHEMBL7261367 0.74 THRB (0.45) ALDH1A1TDP1
SCHEMBL24052904 0.74 ESR1 (0.38) KDM4EPOLBALDH1A1MEN1KMT2A
SCHEMBL16806094 0.73 POLB (0.45) KDM4EPOLBALDH1A1MEN1KMT2A
SCHEMBL5954197 0.73 MEN1 (0.42) KDM4EPOLBALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6852780-B2 Composition for optical material, optical material and lenses NOF CORPORATION (JP) 2005-02-08 US disclosed
US-20030047722-A1 Composition for optical material, optical material and lenses NOF CORPORATION (JP) 2003-03-13 US disclosed
US-6417273-B1 CURABLE MIXTURE OF DI(METH)ACRYLATE, DIVINYLBENZENE OR -BIPHENYL, CROSSLINKING ISOCYANATE, DITHIOL, AND ACCELERATOR; IMPACT STRENGTH, HEAT RESISTANCE; POLYTHIOURETHANES, ADDITION-CONDENSATION COPOLYMERS NOF CORPORATION (JP) 2002-07-09 US disclosed
EP-1116735-A1 MONOMER COMPOSITION FOR OPTICAL PLASTIC MATERIAL, OPTICAL PLASTIC MATERIAL, AND LENS NOF CORPORATION (JP) 2001-07-18 EP disclosed