Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6290863 | 0.96 | POLB (0.44) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL620722 | 0.87 | POLB (0.48) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL17510055 | 0.87 | POLB (0.48) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL4453444 | 0.86 | POLB (0.52) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL31351511 | 0.86 | POLB (0.52) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL19770676 | 0.86 | POLB (0.52) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL16806094 | 0.86 | POLB (0.45) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL6290862 | 0.85 | KDM4E (0.36) | POLBHTTTDP1ELANEKDM4E | |
| SCHEMBL12404381 | 0.85 | THRB (0.49) | THRBPOLBHTTAPEX1TDP1 | |
| SCHEMBL12404362 | 0.85 | THRB (0.49) | THRBPOLBHTTAPEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852780-B2 | Composition for optical material, optical material and lenses | NOF CORPORATION (JP) | 2005-02-08 | — | — | US | disclosed |
| US-20030047722-A1 | Composition for optical material, optical material and lenses | NOF CORPORATION (JP) | 2003-03-13 | — | — | US | disclosed |
| EP-1271186-A1 | COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL AND LENSES | NOF CORPORATION (JP) | 2003-01-02 | — | — | EP | disclosed |