Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP6V1B1 | P15313 | 4/20 | 0.66 |
| ▸ | ATP6AP1 | Q15904 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6296252 | 0.80 | ATP6V1B1 (0.80) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6291933 | 0.79 | ATP6V1B1 (0.94) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6296430 | 0.79 | ATP6V1B1 (0.73) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6292838 | 0.78 | ATP6V1B1 (0.88) | ATP6V1B1ATP6AP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL6291918 | 0.77 | ATP6V1B1 (0.76) | ATP6V1B1 | |
| SCHEMBL6292791 | 0.74 | ATP6V1B1 (0.68) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6296259 | 0.73 | ATP6V1B1 (0.76) | ATP6V1B1ATP6AP1TSHRHSD17B10CYP1A2 | |
| SCHEMBL6292859 | 0.73 | ATP6V1B1 (0.76) | ATP6V1B1ATP6AP1TSHRHSD17B10CYP1A2 | |
| SCHEMBL8344194 | 0.73 | ATP6V1B1 (0.69) | ATP6V1B1ATP6AP1 | |
| SCHEMBL6291639 | 0.72 | ATP6AP1 (0.81) | ATP6V1B1ATP6AP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903117-B2 | Indole derivatives for the treatment of osteoporosis | NIKEM RESEARCH S.R.L. (IT) | 2005-06-07 | — | — | US | disclosed |