Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65415 | 0.83 | THRB (0.36) | THRBTSHRALDH1A1 | |
| SCHEMBL6292049 | 0.82 | THRB (0.42) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL9580207 | 0.81 | THRB (0.46) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL11997925 | 0.80 | THRB (0.43) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL391495 | 0.79 | TSHR (0.36) | THRBTSHR | |
| SCHEMBL203765 | 0.77 | THRB (0.43) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL717628 | 0.77 | THRB (0.53) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL11177282 | 0.75 | HTT (0.33) | THRBHTTALDH1A1 | |
| SCHEMBL1232397 | 0.75 | THRB (0.42) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL1232005 | 0.75 | THRB (0.33) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6852780-B2 | Composition for optical material, optical material and lenses | NOF CORPORATION (JP) | 2005-02-08 | — | — | US | disclosed |
| US-20030047722-A1 | Composition for optical material, optical material and lenses | NOF CORPORATION (JP) | 2003-03-13 | — | — | US | disclosed |
| EP-1271186-A1 | COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL AND LENSES | NOF CORPORATION (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6417273-B1 | CURABLE MIXTURE OF DI(METH)ACRYLATE, DIVINYLBENZENE OR -BIPHENYL, CROSSLINKING ISOCYANATE, DITHIOL, AND ACCELERATOR; IMPACT STRENGTH, HEAT RESISTANCE; POLYTHIOURETHANES, ADDITION-CONDENSATION COPOLYMERS | NOF CORPORATION (JP) | 2002-07-09 | — | — | US | disclosed |
| EP-1116735-A1 | MONOMER COMPOSITION FOR OPTICAL PLASTIC MATERIAL, OPTICAL PLASTIC MATERIAL, AND LENS | NOF CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |