Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27427975 | 0.79 | TSHR (0.49) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL7092835 | 0.77 | THRB (0.76) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL6292018 | 0.77 | THRB (0.51) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL6131096 | 0.76 | THRB (0.39) | THRBTSHRALDH1A1 | |
| SCHEMBL3265039 | 0.75 | THRB (0.73) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL10378212 | 0.75 | TSHR (0.76) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL11600594 | 0.75 | TSHR (0.69) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL1083624 | 0.74 | TSHR (0.75) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL7090691 | 0.74 | TSHR (0.81) | THRBTSHRPOLBAPEX1HTT | |
| Ethyl Acetate SCHEMBL28232168 | 0.74 | THRB (0.70) | THRBTSHRPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8123987-B2 | Chromene compounds | TOKUYAMA CORPORATION (JP) | 2012-02-28 | — | — | US | disclosed |
| US-7951445-B2 | Photochromic optical article and method of producing the same | TOKUYAMA CORPORATION (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20100230648-A1 | Chromene Compounds | TOKUYAMA CORPORATION (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20080226883-A1 | Photochromic Optical Article and Method of Producing the Same | TOKUYAMA CORPORATION (JP) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100230648-A1 | Chromene Compounds | H1-4, RB1, H1-0 | THRB 3240/4885TSHR 1173/4885POLB 1918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.