Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6292198 | 0.92 | CUL4A (0.49) | CUL4AMAPTKLK7KMT2AKDM4E | |
| SCHEMBL6293447 | 0.91 | CUL4A (0.38) | CUL4AMAPTKLK7KMT2AKDM4E | |
| SCHEMBL6297468 | 0.91 | CUL4A (0.38) | CUL4AMAPTKLK7KMT2AKDM4E | |
| SCHEMBL6297245 | 0.85 | CACNA1D (0.41) | CUL4AMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL6293389 | 0.85 | NR3C2 (0.34) | CUL4AMAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL6296757 | 0.83 | ALDH1A1 (0.43) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL6297368 | 0.83 | HSD17B10 (0.36) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL6292239 | 0.82 | NR3C2 (0.40) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL6292466 | 0.82 | ALDH1A1 (0.40) | MAPTKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL6297275 | 0.82 | CDK1 (0.40) | MAPTKMT2AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6977262-B2 | Dihydropyrazolopyridine compounds and pharmaceutical use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2005-12-20 | — | — | US | disclosed |
| US-20040052822-A1 | Dihydropyrazolopyridine compounds and pharmaceutical use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2004-03-18 | — | — | US | disclosed |
| WO-2002062795-A9 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2002-10-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040052822-A1 | Dihydropyrazolopyridine compounds and pharmaceutical use thereof | GSK3B, GSK3A, PYGB | CUL4A 3202/4885MAPT 96/4885KLK7 1499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.