SCHEMBL6292866

SCHEMBL6292866

CCN(Cc1cccc(C(=O)O)c1O)C(=O)CCCCCNC(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.41
CYP3A4 P08684 1/20 0.41
TDP1 Q9NUW8 1/20 0.39
NQO2 P16083 1/20 0.39
CHRM2 P08172 2/20 0.38
CHRM4 P08173 2/20 0.38
CHRM5 P08912 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
SIGMAR1 Q99720 1/20 0.37
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA9 Q16790 3/20 0.37
TPSAB1 Q15661 1/20 0.37
TPSD1 Q9BZJ3 1/20 0.37
TPSG1 Q9NRR2 1/20 0.37
KCNA5 P22460 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6290071 0.81 CYP3A4 (0.56) DRD2CYP3A4TDP1NQO2CHRM2
SCHEMBL8356396 0.77 TDP1 (0.59) CYP3A4TDP1CHRM2CHRM4CHRM5
SCHEMBL8356482 0.77 TDP1 (0.59) CYP3A4TDP1CHRM2CHRM4CHRM5
SCHEMBL6292863 0.76 NAAA (0.44) DRD2CYP3A4TDP1NPSR1CA12
SCHEMBL6290025 0.74 KCNA5 (0.50) NQO2CA12CA1KCNA5
SCHEMBL29347085 0.73 TDP1 (0.51) DRD2CYP3A4TDP1NQO2NPSR1
SCHEMBL6292891 0.73 CHRM2 (0.45) CYP3A4TDP1NQO2CHRM2CHRM4
SCHEMBL31730047 0.72 NQO2 (0.50) DRD2CYP3A4TDP1NQO2NPSR1
SCHEMBL6292867 0.71 CYP3A4 (0.52) DRD2CYP3A4TDP1CA12CA1
SCHEMBL375762 0.71 MEN1 (0.48) DRD2TDP1NQO2NPSR1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6870065-B2 Bifunctional boronic compound complexing reagents and complexes CAMBREX BIO SCIENCE ROCKLAND, INC. (US) 2005-03-22 US disclosed