SCHEMBL6292863

SCHEMBL6292863

CCN(COC(=O)c1ccccc1O)C(=O)CCCCCNC(=O)OC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.44
CYP3A4 P08684 1/20 0.41
TPSAB1 Q15661 1/20 0.41
TPSD1 Q9BZJ3 1/20 0.41
TPSG1 Q9NRR2 1/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
DRD2 P14416 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HTT P42858 1/20 0.38
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6290069 0.81 CYP3A4 (0.52) NAAACYP3A4TPSAB1TPSD1TPSG1
SCHEMBL8356396 0.78 TDP1 (0.59) CYP3A4TDP1CA12CA1CA2
SCHEMBL8356482 0.78 TDP1 (0.59) CYP3A4TDP1CA12CA1CA2
SCHEMBL6292889 0.78 CHRM2 (0.45) CYP3A4TPSAB1TPSD1TPSG1TDP1
SCHEMBL6292866 0.76 DRD2 (0.41) CYP3A4TPSAB1TPSD1TPSG1NPSR1
SCHEMBL6290022 0.73 TDP1 (0.50) KDM4ETDP1L3MBTL1HTTADRB2
SCHEMBL1657927 0.72 ESRRG (0.56) NAAAKDM4EMAPTNPSR1HTT
SCHEMBL28855067 0.72 TDP1 (0.51) CYP3A4KDM4ETDP1CA12CA1
SCHEMBL28855093 0.72 TDP1 (0.51) CYP3A4KDM4ETDP1CA12CA1
SCHEMBL26046370 0.71 NAAA (0.50) NAAACYP3A4KDM4EMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6870065-B2 Bifunctional boronic compound complexing reagents and complexes CAMBREX BIO SCIENCE ROCKLAND, INC. (US) 2005-03-22 US disclosed