SCHEMBL6292889

SCHEMBL6292889

CN(COC(=O)c1c(O)cccc1O)C(=O)CCCCCNC(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.45
CHRM4 P08173 2/20 0.45
CHRM5 P08912 2/20 0.45
CHRM1 P11229 2/20 0.45
CHRM3 P20309 2/20 0.45
CYP3A4 P08684 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
CA1 P00915 9/20 0.42
CA2 P00918 9/20 0.42
CA12 O43570 6/20 0.42
CA9 Q16790 6/20 0.42
TPSAB1 Q15661 1/20 0.41
TPSD1 Q9BZJ3 1/20 0.41
TPSG1 Q9NRR2 1/20 0.41
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40
DRD2 P14416 2/20 0.40
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
SIRT5 Q9NXA8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6292885 0.81 CYP3A4 (0.53) CYP3A4TDP1CA1CA2CA12
SCHEMBL6292863 0.78 NAAA (0.44) CYP3A4TDP1CA1CA2CA12
Hydrochloric Acid SCHEMBL6289936 0.77 CA12 (0.48) CHRM2CHRM1CA1CA2CA12
SCHEMBL6292891 0.76 CHRM2 (0.45) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8354855 0.76 CYP3A4 (0.52) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8356253 0.73 TDP1 (0.63) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL20095815 0.73 TDP1 (0.63) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL24011123 0.73 CYP3A4 (0.46) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8356643 0.72 TDP1 (0.54) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8356644 0.72 TDP1 (0.54) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6870065-B2 Bifunctional boronic compound complexing reagents and complexes CAMBREX BIO SCIENCE ROCKLAND, INC. (US) 2005-03-22 US disclosed