Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27972005 | 0.80 | CES1 (0.57) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL28393908 | 0.79 | CES1 (0.61) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL30196221 | 0.78 | CES1 (0.59) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL1195864 | 0.76 | CES1 (0.57) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL29187272 | 0.74 | CES1 (0.55) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL22319310 | 0.74 | CES1 (0.55) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL28872149 | 0.74 | CES1 (0.50) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL9384330 | 0.73 | CES1 (0.53) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL1042453 | 0.72 | CES1 (1.00) | CES1CES2AKR1B1PAMMEN1 | |
| SCHEMBL5709778 | 0.72 | CES1 (1.00) | CES1CES2AKR1B1PAMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6894181-B2 | Preparation of organohalosilanes | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-05-17 | — | — | US | disclosed |
| US-20030199705-A1 | Preparation of organohalosilanes | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199705-A1 | Preparation of organohalosilanes | NISCH, PDCD2L, STOM | CES1 3086/4885CES2 1886/4885AKR1B1 4333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.