Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29992711 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1GAAHCRTR1HCRTR2 | |
| SCHEMBL1535842 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2ALDH1A1GAAHCRTR1HCRTR2 | |
| SCHEMBL4280858 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL9368406 | 0.78 | CA1 (0.44) | SMN1; SMN2ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9452140 | 0.77 | CA1 (0.40) | SMN1; SMN2ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9743094 | 0.76 | CA1 (0.47) | SMN1; SMN2ALDH1A1GAANPSR1MEN1 | |
| SCHEMBL7064704 | 0.76 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1GAAHCRTR1HCRTR2 | |
| SCHEMBL8089115 | 0.74 | CA1 (0.44) | ALDH1A1GAAMEN1KMT2AMAPT | |
| SCHEMBL8539506 | 0.73 | SMN1; SMN2 (0.32) | SMN1; SMN2TP53GLAMAPT | |
| SCHEMBL9730399 | 0.72 | CA1 (0.45) | SMN1; SMN2ALDH1A1GAANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849578-B1 | Selective herbicides based on 2,6-disubstituted pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2005-02-01 | — | — | US | disclosed |