SCHEMBL7064704

SCHEMBL7064704

CCOC(=O)c1ccccc1S(=O)(=O)N(C(N)=O)c1nc(Cl)cc(OC)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 6/20 0.42
ALDH1A1 P00352 3/20 0.39
TSHR P16473 2/20 0.39
HSD17B10 Q99714 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
RECQL P46063 1/20 0.37
CHRNA7 P36544 1/20 0.37
HCRTR1 O43613 1/20 0.36
HCRTR2 O43614 1/20 0.36
GAA P10253 1/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA12 O43570 1/20 0.36
CA9 Q16790 1/20 0.36
TP53 P04637 2/20 0.36
LMNA P02545 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4280858 0.87 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1TSHRMEN1KMT2A
SCHEMBL1535825 0.84 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1TSHRMEN1KMT2A
SCHEMBL10803109 0.80 CA1 (0.45) SMN1; SMN2ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL9368406 0.79 CA1 (0.44) SMN1; SMN2ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL54939 0.78 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1TSHRMEN1KMT2A
SCHEMBL9452140 0.76 CA1 (0.40) SMN1; SMN2ALDH1A1TSHRMEN1KMT2A
SCHEMBL6054812 0.76 CA1 (0.50) SMN1; SMN2ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL6293979 0.76 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1TSHRMEN1KMT2A
SCHEMBL9743094 0.75 CA1 (0.47) SMN1; SMN2ALDH1A1MEN1KMT2AGAA
SCHEMBL9478884 0.74 TSHR (0.39) SMN1; SMN2ALDH1A1TSHRHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2836072-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT Dongbu Farm Hannong Co., Ltd. (KR) 2015-02-18 EP claimed
WO-2013154396-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2013-10-17 WO claimed
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-11-13 US claimed
US-10206399-B2 Herbicidal composition comprising uracil compound as active ingredient DONGBU FARM HANNONG CO., LTD. (KR) 2019-02-19 US disclosed
EP-2836072-B1 HERBICIDAL COMPOSITION COMPRISING AN URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO LTD (KR) 2018-11-21 EP disclosed
EP-2836072-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT Dongbu Farm Hannong Co., Ltd. (KR) 2015-02-18 EP disclosed
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2015-01-22 US disclosed
WO-2013154396-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT DONGBU FARM HANNONG CO., LTD. (KR) 2013-10-17 WO disclosed
CN-100433978-C Aryl sulfonyl amino carbonyl triazole based selective herbicides BAYER AG (DE) 2008-11-19 CN disclosed
US-5869681-A PREPARING TRIAZOLINONE INTERMEDIATE BY HEATING HYDROCARBYLOXYCARBONYL-ISOSEMICARBAZIDE TO CYCLIZE BAYER AKTIENGESELLSCHAFT (DE) 1999-02-09 US disclosed
US-5780394-A EFFECTIVE AGAINST CHEMICAL RESISTANT PESTS; PESTICIDES, HERBIDES BAYER AKTIENGESELLSCHAFT (DE) 1998-07-14 US disclosed
US-5739389-A INSECTICIDE; HERBICIDE BAYER AKTIENGESELLSCHAFT (DE) 1998-04-14 US disclosed
CN-1035753-A Make cultivated plant avoid the thiazole-5-Carboxylamide of highy potent herbicide to the plant poisoning effect CIBA GEIGY AG (CH) 1989-09-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides AADAC, CBR3, ABAT SMN1; SMN2 3410/4885ALDH1A1 591/4885TSHR 1633/4885
US-20150024940-A1 HERBICIDAL COMPOSITION COMPRISING URACIL COMPOUND AS ACTIVE INGREDIENT UNG, DDT, HDHD5 SMN1; SMN2 3221/4885ALDH1A1 474/4885TSHR 4656/4885
US-10206399-B2 Herbicidal composition comprising uracil compound as active ingredient UNG, DDT, HDHD5 SMN1; SMN2 3221/4885ALDH1A1 474/4885TSHR 4656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.