Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 7/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | MATK | P42679 | 1/20 | 0.39 |
| ▸ | FRK | P42685 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6291171 | 0.87 | HSP90AA1 (0.45) | MAPK14MAPK13MAPK12MAPK11HSP90AA1 | |
| SCHEMBL6294273 | 0.85 | FGFR1 (0.46) | MAPK14MAPK13MAPK12MAPK11HSP90AA1 | |
| SCHEMBL6291235 | 0.81 | PTGS2 (0.59) | PTGS1PTGS2 | |
| SCHEMBL19953122 | 0.80 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1CYP11B1CYP11B2FLT3 | |
| SCHEMBL25611833 | 0.80 | FLT3 (0.47) | MAPK14MAPK13MAPK12MAPK11HSP90AA1 | |
| SCHEMBL10773460 | 0.80 | FLT3 (0.55) | MAPK14MAPK13MAPK12MAPK11HSP90AA1 | |
| SCHEMBL6180422 | 0.77 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1PTGS1CYP11B1CYP11B2 | |
| SCHEMBL6180979 | 0.77 | PTGS2 (0.63) | PTGS1PTGS2 | |
| SCHEMBL6294248 | 0.77 | PTGS2 (0.63) | PTGS1PTGS2 | |
| SCHEMBL6178361 | 0.77 | HSP90AA1 (0.40) | MAPK14MAPK13MAPK12MAPK11HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6838476-B1 | Cyclooxygenase inhibitors; anticancer agents | J. URIACH & CIA, SA (ES) | 2005-01-04 | — | — | US | disclosed |
| EP-1122243-B1 | NOVEL IMIDAZOLES WITH ANTI-INFLAMMATORY ACTIVITY | URIACH Y COMPANIA S A J (ES) | 2004-09-08 | — | — | EP | disclosed |
| EP-1122243-A1 | NOVEL IMIDAZOLES WITH ANTI-INFLAMMATORY ACTIVITY | J. URIACH & CIA. S.A. (ES) | 2001-08-08 | — | — | EP | disclosed |