Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | F3 | P13726 | 5/20 | 0.38 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | F7 | P08709 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.38 |
| ▸ | PLG | P00747 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300656 | 0.87 | F3 (0.42) | F3F2F7F10PLG | |
| SCHEMBL6300738 | 0.84 | F3 (0.41) | F3F2F7F10PLG | |
| SCHEMBL6300609 | 0.78 | PYGL (0.38) | PYGLSCN9AMAPTALDH1A1 | |
| SCHEMBL6295760 | 0.77 | F3 (0.43) | F3F2F7F10PLG | |
| SCHEMBL6300657 | 0.74 | PYGL (0.52) | PYGLSMN1; SMN2 | |
| SCHEMBL6294962 | 0.73 | PYGL (0.40) | PYGLLMNASCN9AMAPTALDH1A1 | |
| SCHEMBL6294722 | 0.73 | PYGL (0.42) | PYGLLMNASCN9AMAPTALDH1A1 | |
| SCHEMBL6294975 | 0.72 | PYGL (0.42) | PYGLLMNAF10MAPTALDH1A1 | |
| SCHEMBL6300708 | 0.72 | MAPT (0.36) | PYGLLMNASCN9AMAPTALDH1A1 | |
| SCHEMBL6300732 | 0.71 | F3 (0.46) | F3F2F7F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20030181766-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181766-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | F2, SERPINC1, F12 | PYGL 1434/4885LMNA 1305/4885F3 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.