SCHEMBL62949

SCHEMBL62949

C=CC(=O)OC(C(F)(F)F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.35
ALDH1A1 P00352 4/20 0.34
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HSD17B10 Q99714 1/20 0.33
ABHD6 Q9BV23 3/20 0.31
HPGD P15428 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26362999 0.87 TSHR (0.35) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16409377 0.87 TSHR (0.31) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL25962745 0.84 TSHR (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9244581 0.84 CA1 (0.32) ALDH1A1CA1CA2CA9
SCHEMBL30578066 0.84
SCHEMBL3180520 0.82
SCHEMBL15435723 0.82 THRB (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28950365 0.82 ABHD6 (0.33) TSHRABHD6
SCHEMBL15295498 0.82 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1902919 0.80 HCAR2 (0.39) ABHD6CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1488 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747311-A1 PERFLUOROPOLYETHER COPOLYMERS FOR BIOMEDICAL APPLICATIONS Axoft, Inc. (US) 2026-05-27 EP claimed
WO-2026102880-A1 FULL-TEMPERATURE-RANGE POLYMER-BASED SOLID ELECTROLYTE, SOLID-STATE BATTERY AND PREPARATION METHOD 固态离子能源科技(武汉)有限公司 2026-05-21 WO claimed
EP-4673050-A1 METHODS TO CONNECT FREE-STANDING SOFT NEURAL PROBES TO ACTIVE ELECTRONIC DEVICES WITH HIGH CHANNEL COUNT INTERFACE Axoft, Inc. (US) 2026-01-07 EP claimed
US-12364424-B2 Fluorinated elastomers for brain probes and other applications PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-07-22 US claimed
CN-119994191-A Electrolyte for high voltage and lithium ion battery 清陶(昆山)能源发展集团股份有限公司 2025-05-13 CN claimed
CN-119905656-A Electrolyte, preparation method of electrolyte and lithium ion battery 惠州亿纬锂能股份有限公司 2025-04-29 CN claimed
CN-119875000-A Method for reducing the residual monomer content in a polymer composition, composition capable of free radical polymerization, method for producing a polymer, polymer and use 沈阳康恩德医疗科技有限公司 2025-04-25 CN claimed
WO-2025082503-A1 APOPTOSIS INHIBITOR MOLYBDATE SALTS FOR TREATING CANCER JIANG CHUN (US) 2025-04-24 WO claimed
WO-2025081428-A1 APOPTOSIS INHIBITOR MOLYBDATE SALTS FOR TREATING CANCER JIANG CHUN (US) 2025-04-24 WO claimed
CN-119592083-A Low-cost double-network fluorosilicone rubber and preparation method thereof 深圳市泰美斯科技有限公司 2025-03-11 CN claimed
EP-0406161-A2 Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof CIBA-GEIGY AG (CH) 1991-01-02 EP claimed
EP-0380667-A1 ULTRAVIOLET-ABSORBING POLYMER MATERIAL AND PHOTOETCHING PROCESS TERUMO KABUSHIKI KAISHA (JP) 1990-08-08 EP claimed
US-4904421-A SOFT POLYMER LENS IMPREGNATED WITH A MONOMER WHICH IS THEN POLYMERIZED TO FORM A HARD POLYMER BLEND; MACHINING; REMOVAL OF HARD POLYMER. TOMEI SANGYO KABUSHIKI KAISHA (JP) 1990-02-27 US claimed
EP-0351364-A2 Dimethylacrylamide-copolymer hydrogels with high oxygen permeability CIBA-GEIGY AG (CH) 1990-01-17 EP claimed
EP-0318604-A1 Soft ocular lens and method for its preparation Tomei Sangyo Kabushiki Kaisha (JP) 1989-06-07 EP claimed
EP-0050934-B1 FLUORINE-CONTAINING HYDROGEL-FORMING POLYMERIC MATERIALS KELVIN LENSES LIMITED (GB) 1986-05-28 EP claimed
US-4493910-A COPOLYMER OF UNSATURATED AMIDE, N-VINYL LACTAM, UNSATURATED CARBOX KELVIN LENSES LIMITED (GB) 1985-01-15 US claimed
US-4433111-A CONTACT LENSES, EXTENDED WEAR KELVIN LENSES LIMITED (GB) 1984-02-21 US claimed
EP-0050934-A1 Fluorine-containing hydrogel-forming polymeric materials KELVIN LENSES LIMITED (GB) 1982-05-05 EP claimed
US-4266015-A SILVER HALIDE EMULSIONS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1981-05-05 US claimed