Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.59 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.55 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.53 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.53 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301809 | 0.89 | ESR1 (0.60) | ESR1KEAP1NFE2L2TSHRMAPK1 | |
| SCHEMBL3257686 | 0.84 | ACHE (0.73) | ESR1C5AR1ACHEKEAP1NFE2L2 | |
| SCHEMBL3257523 | 0.83 | C5AR1 (0.82) | ESR1C5AR1ACHEKEAP1NFE2L2 | |
| SCHEMBL1688338 | 0.81 | KMT2A (0.63) | ESR1C5AR1PSEN1PSEN2APH1B | |
| SCHEMBL3257725 | 0.80 | C5AR1 (0.77) | C5AR1TSHRMMP2MMP9 | |
| SCHEMBL12482378 | 0.79 | C5AR1 (0.53) | ESR1C5AR1PSEN1PSEN2APH1B | |
| SCHEMBL5604160 | 0.78 | ESR1 (0.73) | ESR1KEAP1NFE2L2CNR1CNR2 | |
| SCHEMBL12481734 | 0.77 | ESR1 (0.60) | ESR1C5AR1PSEN1PSEN2APH1B | |
| SCHEMBL12482026 | 0.77 | C5AR1 (0.50) | ESR1C5AR1PSEN1PSEN2APH1B | |
| SCHEMBL30582418 | 0.75 | C5AR1 (0.48) | ESR1C5AR1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921740-B1 | Electron-receiving compound and thermal recording material | MITSUBISHI PAPER MIILS LTD. (JP) | 2005-07-26 | — | — | US | disclosed |