Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.60 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 2/20 | 0.49 |
| ▸ | RORA | P35398 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | RORB | Q92753 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6295477 | 0.89 | ESR1 (0.59) | ESR1TSHRMAPK1KMT2AHSD17B10 | |
| SCHEMBL6297127 | 0.82 | ESR1 (0.59) | ESR1NR1I2KMT2AMMP2MMP9 | |
| SCHEMBL6301696 | 0.80 | C5AR1 (0.62) | ESR1KMT2AKEAP1NFE2L2 | |
| SCHEMBL3260769 | 0.77 | C5AR1 (0.58) | NR1I2TSHRMMP2MMP9NR1H2 | |
| SCHEMBL6428043 | 0.77 | ESR1 (0.77) | ESR1NR1I2TSHRMAPK1KMT2A | |
| SCHEMBL6302204 | 0.77 | ESR1 (0.88) | ESR1NR1I2TSHRMAPK1KMT2A | |
| SCHEMBL3257686 | 0.76 | ACHE (0.73) | ESR1KMT2AMMP9KEAP1NFE2L2 | |
| SCHEMBL10904389 | 0.73 | ESR1 (1.00) | ESR1NR1I2TSHRMAPK1KMT2A | |
| SCHEMBL6297282 | 0.73 | ESR1 (0.70) | ESR1NR1I2TSHRMAPK1KMT2A | |
| SCHEMBL1688338 | 0.73 | KMT2A (0.63) | ESR1KMT2AHSD17B10KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921740-B1 | Electron-receiving compound and thermal recording material | MITSUBISHI PAPER MIILS LTD. (JP) | 2005-07-26 | — | — | US | disclosed |