Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225645 | 0.80 | MAPT (0.36) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL2059403 | 0.77 | TSHR (0.40) | TSHRHCAR2 | |
| SCHEMBL2086712 | 0.75 | CA1 (0.33) | — | |
| SCHEMBL4953905 | 0.75 | TDP1 (0.39) | TSHR | |
| SCHEMBL5872657 | 0.71 | TSHR (0.34) | TSHR | |
| SCHEMBL5872641 | 0.70 | NAAA (0.43) | TSHRHCAR2 | |
| SCHEMBL5860646 | 0.70 | — | — | |
| SCHEMBL5428033 | 0.69 | TSHR (0.33) | TSHRHCAR2 | |
| SCHEMBL1788899 | 0.68 | LMNA (0.35) | TSHR | |
| SCHEMBL2822436 | 0.67 | TSHR (0.39) | TSHRHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514542-B1 | Medicinal composition comprising Tacrine or Donepezil for improving brain function. | TOYAMA CHEMICAL CO LTD (JP) | 2012-02-22 | — | — | EP | claimed |