SCHEMBL629578

SCHEMBL629578

O=CCC1C=Cc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.49
HTR2A P28223 2/20 0.38
SIGMAR1 Q99720 6/20 0.38
KDM4E B2RXH2 2/20 0.32
CYP2D6 P10635 2/20 0.32
BRD4 O60885 1/20 0.32
CCL2 P13500 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CHRM2 P08172 1/20 0.32
CYP3A4 P08684 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
NFKB1 P19838 1/20 0.32
CHRM3 P20309 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7762670 0.84 HTR6 (0.51) HTR6HTR2ASIGMAR1KDM4ECYP2D6
SCHEMBL132480 0.84 HTR6 (0.51) HTR6HTR2ASIGMAR1KDM4ECYP2D6
SCHEMBL15224275 0.84 HTR6 (0.38) HTR6SIGMAR1LMNARETSMN1; SMN2
SCHEMBL292407 0.81 HTR6 (0.49) HTR6HTR2ASIGMAR1KDM4ECYP2D6
SCHEMBL1779074 0.81 HTR6 (0.49) HTR6HTR2ASIGMAR1KDM4ECYP2D6
SCHEMBL1453509 0.79 HTR6 (0.58) HTR6HTR2ASIGMAR1KDM4ECYP2D6
SCHEMBL5917333 0.79 HTR6 (0.31) HTR6
SCHEMBL7385660 0.78 HTR6 (0.46) HTR6HTR2ASIGMAR1KDM4ECYP2D6
SCHEMBL7385663 0.78 HTR6 (0.46) HTR6HTR2ASIGMAR1KDM4ECYP2D6
SCHEMBL7627841 0.78 HTR6 (0.46) HTR6HTR2ASIGMAR1KDM4ECYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108445168-B Method for rapidly detecting and judging solid acetic acid fermented unstrained spirits in vinegar brewing 山西梁汾金龙鱼醋业有限公司 2021-03-26 CN disclosed
CN-108445168-A Solid-state acetic fermentation quickly detects determination method at unstrained spirits in a kind of vinegar brewing 山西梁汾醋业有限公司 2018-08-24 CN disclosed
EP-2419403-A1 VITAMIN D RECEPTOR AGONISTS AND USES THEREOF Vidasym, Llc (US) 2012-02-22 EP disclosed
CN-1107844-A Indane derivative, processes for preparing the same and synthetic intermediate of the same TANABE SEIYAKU CO (JP) 1995-09-06 CN disclosed
US-5091387-A Spirocyclic oxytocin antagonists MERCK & CO., INC. (US) 1992-02-25 US disclosed
EP-0450761-A1 Spirocyclic oxytocin antagonists MERCK & CO. INC. (US) 1991-10-09 EP disclosed
EP-0444945-A2 Use of spirocyclic compounds as oxytocin antagonists MERCK & CO. INC. (US) 1991-09-04 EP disclosed