Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762670 | 1.00 | HTR6 (0.51) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL11576712 | 0.89 | HTR6 (0.50) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL11414399 | 0.89 | HTR6 (0.46) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL8427938 | 0.86 | HTR6 (0.44) | HTR6HTR2ASIGMAR1KDM4E | |
| SCHEMBL8425581 | 0.86 | HTR6 (0.44) | HTR6HTR2ASIGMAR1KDM4E | |
| SCHEMBL11575785 | 0.84 | HTR6 (0.43) | HTR6HTR2ASIGMAR1 | |
| SCHEMBL629578 | 0.84 | HTR6 (0.49) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL1779074 | 0.84 | HTR6 (0.49) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL292407 | 0.84 | HTR6 (0.49) | HTR6HTR2ASIGMAR1KDM4ELMNA | |
| SCHEMBL1453509 | 0.82 | HTR6 (0.58) | HTR6HTR2ASIGMAR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235069-B1 | NANO-LINKED METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL CO (US) | 2015-11-25 | — | — | EP | disclosed |
| US-8524626-B2 | Nano-linked metallocene catalyst compositions and their polymer products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2013-09-03 | — | — | US | disclosed |
| US-20120058886-A1 | Nano-Linked Metallocene Catalyst Compositions and Their Polymer Products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2012-03-08 | — | — | US | disclosed |
| US-8080681-B2 | Nano-linked metallocene catalyst compositions and their polymer products | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2011-12-20 | — | — | US | disclosed |
| US-20090171041-A1 | NANO-LINKED METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | CHEVRON PHILLIPS CHEMICAL COMPANY (US) | 2009-07-02 | — | — | US | disclosed |
| EP-0752428-B1 | Metallocene catalyst for the (co)polimerization of alpha-olefins | ENICHEM SPA (IT) | 2001-04-04 | — | — | EP | disclosed |
| US-5753578-A | ADDITION POLYMERIZATION CATALYSTS CONTAINING A CO-CATALYST | ENICHEM S.P.A. (IT) | 1998-05-19 | — | — | US | disclosed |
| EP-0752428-A2 | Metallocene catalyst for the (co)polimerization of alpha-olefins | ENICHEM S.p.A. (IT) | 1997-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090171041-A1 | NANO-LINKED METALLOCENE CATALYST COMPOSITIONS AND THEIR POLYMER PRODUCTS | NCL, CPNE4, NDC1 | HTR6 3790/4885HTR2A 3671/4885SIGMAR1 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.