Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.83 |
| ▸ | RAB9A | P51151 | 13/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.83 |
| ▸ | TP53 | P04637 | 4/20 | 0.83 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.83 |
| ▸ | ATM | Q13315 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5797611 | 0.98 | NPC1 (0.81) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL6799157 | 0.91 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL22495269 | 0.88 | RAB9A (0.79) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL18938399 | 0.88 | RAB9A (0.79) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL1918108 | 0.87 | NPC1 (0.81) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL27181622 | 0.87 | KMT2A (0.75) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL27180643 | 0.87 | KMT2A (0.75) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL30341896 | 0.86 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL22192206 | 0.86 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 | |
| SCHEMBL8769709 | 0.86 | RAB9A (0.89) | NPC1RAB9ASMN1; SMN2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139435-A1 | PROSTAGLANDIN ANALOGS AND USES THEREOF | Lifex Biolabs, Inc. | 2021-05-13 | — | — | US | disclosed |
| US-6897316-B2 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | CHINA MEDICAL UNIVERSITY (TW) | 2005-05-24 | — | — | US | disclosed |
| US-20050032832-A1 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | CHINA MEDICAL UNIVERSITY (TW) | 2005-02-10 | — | — | US | disclosed |
| US-4160862-A | ANTIINFLAMMATORY | STERLING DRUG INC. (US) | 1979-07-10 | — | — | US | disclosed |
| US-4021431-A | ANTIINFLAMMATORY AGENTS | STERLING DRUG INC. (US) | 1977-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139435-A1 | PROSTAGLANDIN ANALOGS AND USES THEREOF | PTGDR, NR3C1, PTGIR | NPC1 1626/4885RAB9A 1564/4885SMN1; SMN2 1291/4885 |
| US-20050032832-A1 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CHUK | NPC1 1739/4885RAB9A 1223/4885SMN1; SMN2 3038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.