Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 6/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300632 | 0.90 | PLA2G7 (0.43) | PLA2G7 | |
| Trifluoroacetic Acid SCHEMBL6296006 | 0.89 | BRD4 (0.43) | BRD4SCN9ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6295010 | 0.89 | PLA2G7 (0.44) | PLA2G7TBXA2R | |
| SCHEMBL6300709 | 0.88 | PLA2G7 (0.46) | BRD4PLA2G7PGR | |
| Trifluoroacetic Acid SCHEMBL6300629 | 0.79 | PLA2G7 (0.44) | PLA2G7 | |
| Trifluoroacetic Acid SCHEMBL6295008 | 0.78 | PLA2G7 (0.46) | PLA2G7TBXA2R | |
| Trifluoroacetic Acid SCHEMBL6300704 | 0.77 | PLA2G7 (0.47) | PLA2G7PGR | |
| Trifluoroacetic Acid SCHEMBL7153144 | 0.76 | BRD4 (0.43) | BRD4SCN9APLA2G7PGRAR | |
| SCHEMBL6294970 | 0.73 | SCN9A (0.41) | SCN9ATBXA2R | |
| Trifluoroacetic Acid SCHEMBL7153794 | 0.72 | BRD4 (0.40) | BRD4SCN9ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |