Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 11/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6295008 | 0.92 | PLA2G7 (0.46) | PLA2G7ATMMEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6300629 | 0.92 | PLA2G7 (0.44) | PLA2G7ATMALDH1A1 | |
| SCHEMBL6300709 | 0.90 | PLA2G7 (0.46) | PLA2G7ATMPGRMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL6296006 | 0.88 | BRD4 (0.43) | PLA2G7ATM | |
| SCHEMBL6300632 | 0.81 | PLA2G7 (0.43) | PLA2G7 | |
| SCHEMBL6295010 | 0.81 | PLA2G7 (0.44) | PLA2G7ATMMEN1KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7155223 | 0.77 | PLA2G7 (0.43) | PLA2G7MEN1KMT2A | |
| SCHEMBL6296007 | 0.77 | BRD4 (0.42) | PLA2G7PGR | |
| Trifluoroacetic Acid SCHEMBL7150647 | 0.75 | PLA2G7 (0.44) | PLA2G7MEN1KMT2AALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL7155334 | 0.73 | PLA2G7 (0.40) | PLA2G7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |