Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ASPH | Q12797 | 3/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | AGER | Q15109 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801476 | 1.00 | HTT (0.37) | HTTHSD17B10GLATLR7KDM4E | |
| SCHEMBL30779709 | 0.83 | KDM4E (0.44) | HTTHSD17B10GLATLR7KDM4E | |
| SCHEMBL630383 | 0.83 | KDM4E (0.44) | HTTHSD17B10GLATLR7KDM4E | |
| SCHEMBL4570471 | 0.81 | HTT (0.38) | HTTHSD17B10GLATLR7KDM4E | |
| Hydrochloric Acid SCHEMBL629621 | 0.81 | KDM4E (0.42) | HTTHSD17B10GLATLR7KDM4E | |
| SCHEMBL29936207 | 0.79 | ADORA3 (0.41) | HTTHSD17B10GLATLR7KDM4E | |
| SCHEMBL4570470 | 0.79 | GLA (0.38) | HTTHSD17B10GLATLR7KDM4E | |
| SCHEMBL212115 | 0.79 | ADORA3 (0.41) | HTTHSD17B10GLATLR7KDM4E | |
| SCHEMBL698878 | 0.77 | TSHR (0.37) | TLR7KDM4EASPHKDM8MAPT | |
| SCHEMBL23221405 | 0.75 | TLR7 (0.39) | HTTHSD17B10GLATLR7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551037-A | Compounds as succinate dehydrogenase inhibitors and uses thereof | 华东理工大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-111454202-B | Heteroaryl formanilide compound containing pentafluorothio and preparation method and application thereof | 山东省联合农药工业有限公司 | 2021-10-01 | — | — | CN | disclosed |
| CN-110818637-B | Substituted amide compound and preparation method and application thereof | 山东省联合农药工业有限公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-110818637-A | Substituted amide compound and preparation method and application thereof | 山东省联合农药工业有限公司 | 2020-02-21 | — | — | CN | disclosed |
| US-8168638-B2 | Pyrazinecarboxamide derivatives and plant disease controlling agents containing the same | NIHON NOHYAKU CO., LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| EP-1963286-B1 | PYRAZINECARBOXAMIDE DERIVATIVES AND PLANT DISEASE CONTROLLING AGENTS CONTAINING THE SAME | NIHON NOHYAKU CO LTD (JP) | 2012-02-22 | — | — | EP | disclosed |
| CN-101341136-B | Pyrazinecarboxamide derivatives and plant disease controlling agents containing the same | NIHON NOHYAKU CO LTD | 2011-07-06 | — | — | CN | disclosed |
| US-20090233934-A1 | Pyrazinecarboxamide Derivatives and Plant Disease Controlling Agents Containing the Same | NIHON NOHYAKU CO., LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| CN-101341136-A | Pyrazinecarboxamide derivatives and plant disease controlling agents containing the same | NIHON NOHYAKU CO LTD (JP) | 2009-01-07 | — | — | CN | disclosed |
| EP-1963286-A1 | PYRAZINECARBOXAMIDE DERIVATIVES AND PLANT DISEASE CONTROLLING AGENTS CONTAINING THE SAME | Nihon Nohyaku Co., Ltd. (JP) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007072999-A1 | PYRAZINECARBOXAMIDE DERIVATIVES AND PLANT DISEASE CONTROLLING AGENTS CONTAINING THE SAME | NIHON NOHYAKU CO., LTD (JP) | 2007-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233934-A1 | Pyrazinecarboxamide Derivatives and Plant Disease Controlling Agents Containing the Same | CBR3, CNPY2, AADAC | HTT 899/4885HSD17B10 2967/4885GLA 2827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.